ChemicalBook--->CAS DataBase List--->4546-72-9

4546-72-9

4546-72-9 Structure

4546-72-9 Structure
IdentificationMore
[Name]

N-Benzoyl-2'-deoxy-adenosine
[CAS]

4546-72-9
[Synonyms]

DA-BZ
N6-BENZOYL-2'-DEOXYADENOSINE
N6-BENZOYLDEOXYADENOSINE
N6-BZ-2'-DEOXYADENOSINE
n-benzoyl-2'-deoxy-adenosine
N-BZ-DA
n-benzoyl-2’-deoxy-adenosin
BZ-DEOXYADENOSINE
DA-BZ 99.0%
N(sup 6)benzoyl-2'-deoxyadenosine
N-[9-(2-Deoxy-β-D-ribofuranosyl)-9H-purine-6-yl]benzamide
[EINECS(EC#)]

224-903-6
[Molecular Formula]

C17H17N5O4
[MDL Number]

MFCD00009628
[Molecular Weight]

355.35
[MOL File]

4546-72-9.mol
Chemical PropertiesBack Directory
[Melting point ]

120-122C
[density ]

1.61±0.1 g/cm3(Predicted)
[storage temp. ]

Store at 0°C
[pka]

7.87±0.43(Predicted)
[Water Solubility ]

Soluble in water (slightly), and methanol (20 mg/ml).
[CAS DataBase Reference]

4546-72-9(CAS DataBase Reference)
Safety DataBack Directory
[Safety Statements ]

24/25
[HS Code ]

29349990
Hazard InformationBack Directory
[Description]

N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.
[Uses]

Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.
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