| Identification | More | [Name]
Pseudohypericin | [CAS]
55954-61-5 | [Synonyms]
PSEUDOHYPERICIN
Phenanthro[1,10,9,8-opqra]perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-
1,3,4,6,8,13-Hexahydroxy-10-(hydroxymethyl)-11-methylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
1,3,4,6,8,13-Hexahydroxy-10-hydroxymethyl-11-methylphenanthro[1,10,9,8-opqra]perylene-7,14-dione | [Molecular Formula]
C30H16O9 | [MDL Number]
MFCD00133794 | [Molecular Weight]
520.44 | [MOL File]
55954-61-5.mol |
| Hazard Information | Back Directory | [Uses]
Pseudohypericin is a specific inhibitor of protein kinase C and D-β-Hydroxylase. Also, it is used in determination of potential drug candidate molecules of Hypericum perforatum for COVID-19 treatment. | [Definition]
ChEBI: Pseudohypericin is an ortho- and peri-fused polycyclic arene. | [Enzyme inhibitor]
This anti-retroviral agent (FW = 520.45 g/mol) inhibits protein kinase C with an IC50 value of 28.7 μM and dopamine b-hydroxylase with IC50 = 3 μM. Pseudohypericin is a component of St. John’s Wort (Hypericum perforatum). Target(s): dopamine b-hydroxylase; inositoltrisphosphate 3-kinase; and protein kinase C. |
|
|