| Identification | More | [Name]
(-)-8-PHENYLMENTHOL | [CAS]
65253-04-5 | [Synonyms]
(-)-PHENMENTHOL
(-)-8-PHENYLMENTHOL
(-)-8-Phenylmenthol,98%
(-)-8-Phenylmenthol,97%
(-)-8-Phenylmenthol 98%
(-)-8-Phenylmenthol, GC 97%
(1R,2S,5R)-5-Methyl-2-(2-phenylpropan-2-yl)cyclohexanol
(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol
5-METHYL-2-(1-METHYL-1-PHENYLETHYL)-(1R,2S,5R)-CYCLOHEXANOL
Cyclohexanol, 5-methyl-2-(1-methyl-1-phenylethyl)-, (1R,2S,5R)- | [Molecular Formula]
C16H24O | [MDL Number]
MFCD00010501 | [Molecular Weight]
232.36 | [MOL File]
65253-04-5.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS OILY LIQUID | [alpha ]
-26°(20/D, c=2, C2H5OH) | [Boiling point ]
130 °C (0.7501 mmHg) | [density ]
0.999 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.53(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [form ]
Viscous Liquid | [pka]
15.21±0.60(Predicted) | [color ]
Clear colorless to light yellow | [Specific Gravity]
0.999 | [optical activity]
[α]20/D 26°, c = 2 in ethanol | [λmax]
259nm(CH2Cl2)(lit.) | [BRN ]
3651167 | [CAS DataBase Reference]
65253-04-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
3-8-10 | [HS Code ]
29061900 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS OILY LIQUID | [Uses]
(-)-8-Phenylmenthol is used to prepare piperidine-based analogs of cocaine as monoamine reuptake inhibitors. It is also used to prepare quinuclidinyl (fluoroalkyl)benzilate as muscarinic receptor antagonist. | [Purification Methods]
Dissolve the menthol in toluene, dry (Na2SO4), evaporate and chromatograph it on a silica gel column and eluting with 5% Et2O in pet ether to give an oil with the desired rotation. IR has max 3420cm-1 (OH) with consistent 1H NMR [Corey & Ensley J Org Chem 43 1610 1978, Whitesell et al. Tetrahedron 42 2993 1986, Bednarski & Danishefsky J Am Chem Soc 108 7060 1986]. |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
TCI Chemicals
|
| Tel: |
021-67121386, 800-988-0390 |
| Website: |
www.tcichemicals.com |
|