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82547-58-8

82547-58-8 Structure

82547-58-8 Structure
IdentificationMore
[Name]

Cefteram pivoxil
[CAS]

82547-58-8
[Synonyms]

CEFTERAM
2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetylamino]-3-(5-methyl-2H-tetrazol-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Cefteram pivoxil
(+)-(6R,7R)-7-[(Z)-2-(2-Amincr4-thiazolyl)-2-(methoxyimino)acetami-do]-3-[(5-methyl-2H-tetrazol-2-y1)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Ceftetrame
Ro-19-5247
T-2525
Tomimn
(6R,6β)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
[6R,7R,(+)]-7α-[[2-(2-Aminothiazol-4-yl)-2-[(Z)-methoxyimino]acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Antibiotic Ro-19-5247
[Molecular Formula]

C16H17N9O5S2
[MDL Number]

MFCD00864913
[Molecular Weight]

479.49
[MOL File]

82547-58-8.mol
Chemical PropertiesBack Directory
[Melting point ]

>175°C (dec.)
[density ]

1.95±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

2.62±0.50(Predicted)
[color ]

White to Pale Yellow
[InChIKey]

XSPUSVIQHBDITA-RKYNPMAHSA-N
[SMILES]

N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(CN1N=NC(C)=N1)=C2C(O)=O
[CAS DataBase Reference]

82547-58-8(CAS DataBase Reference)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Trifluoroacetic acid-->Sulfolane-->7-Aminocephalosporanic acid-->Tetrazole-->TRIMETHYLSILANE
[Preparation Products]

Cefteram pivoxil
Hazard InformationBack Directory
[Description]

Cefteram pivoxil is an orally-active cephalosponn antibiotic with a broad spectrum of activity. It is reportedly effective against Cirrobacrer, indole-positive Proreus and Enrerobacrer species resistant to cefaclor, cephalexin and amoxicillin. Cefteram pivoxil is indicated primarily for urinary tract infections.
[Chemical Properties]

Pale Yellow Solid
[Originator]

Toyama (Japan)
[Uses]

Orally active cephalosporin antibiotic, antibacterial.
[Definition]

ChEBI: Cefteram is a cephalosporin compound having (5-methyl-2H-tetrazol-2-yl)methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups; a third-generation cephalosporin antibiotic.
[Brand name]

Tomiron
[Antimicrobial activity]

A semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefteram pivoxil. Activity is similar to that of cefixime, but with slightly better activity against staphylococci and some Gram-negative rods.
Available in Japan.
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