| Identification | More | [Name]
Tributylphosphane | [CAS]
998-40-3 | [Synonyms]
CYTOP(R) 340
LABOTEST-BB LT01408514
PHOSPHINE, TRIBUTYL
PHOSPHORUS TRI-N-BUTYL
TBP
TBUP
tributylphosphane
TRIBUTYLPHOSPHINE
TRI-N-BUTYLPHOSPHINE
tris(butyl)phosphine
(n-C4H9)3P
Tributylfosfin
tributyl-phosphin
Tributylphosphorus
TRIBUTYL PHOSPHINE (CYTOP 340) CYTEC QUALITY
Tri-n-butylphosphine,95%
Tri-n-butylphosphine,99%
Tri-n-butylphosphine,99%(10wt%inhexane)
Tri-n-butylphosphine,min.93%
cytop 340 | [EINECS(EC#)]
213-651-2 | [Molecular Formula]
C12H27P | [MDL Number]
MFCD00009462 | [Molecular Weight]
202.32 | [MOL File]
998-40-3.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear liquid | [Melting point ]
-65 °C
| [Boiling point ]
150 °C50 mm Hg(lit.)
| [density ]
0.81 g/mL at 25 °C(lit.)
| [vapor density ]
9 (vs air)
| [vapor pressure ]
1.9Pa at 20℃ | [refractive index ]
n20/D 1.462(lit.)
| [Fp ]
99 °F
| [storage temp. ]
2-8°C
| [form ]
liquid
| [color ]
Clear colorless to pale yellow | [Specific Gravity]
0.820 (20/4℃) | [Stability:]
Stable, but pyrophoric-spontaneously inflammable in air. Incompatible with oxidizing agents. Moisture sensitive. | [Water Solubility ]
insoluble | [Sensitive ]
Moisture Sensitive/Air Sensitive | [BRN ]
1738261 | [InChIKey]
TUQOTMZNTHZOKS-UHFFFAOYSA-N | [CAS DataBase Reference]
998-40-3(CAS DataBase Reference) | [NIST Chemistry Reference]
Phosphine, tributyl-(998-40-3) | [EPA Substance Registry System]
998-40-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,F,C | [Risk Statements ]
R36/38:Irritating to eyes and skin .
R34:Causes burns.
R21/22:Harmful in contact with skin and if swallowed .
R17:Spontaneously flammable in air.
R11:Highly Flammable.
R37:Irritating to the respiratory system. | [Safety Statements ]
S41:In case of fire and/or explosion do not breathe fumes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S16:Keep away from sources of ignition-No smoking .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S43:In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add-Never use water) .
S17:Keep away from combustible material .
S5:Keep contents under ... (appropriate liquid to be specified by the manufacturer) . | [RIDADR ]
UN 3254 4.2/PG 1
| [WGK Germany ]
3
| [RTECS ]
SZ3270000
| [F ]
10-13-23 | [Autoignition Temperature]
392 °F | [TSCA ]
Yes | [HazardClass ]
4.2 | [PackingGroup ]
I | [HS Code ]
29319090 |
| Hazard Information | Back Directory | [General Description]
TRIBUTYLPHOSPHINE(998-40-3) is a colorless to yellowish liquid with a strong garlic-like odor. TRIBUTYLPHOSPHINE(998-40-3) is insoluble in water. TRIBUTYLPHOSPHINE(998-40-3) is liable to heat and ignite spontaneously in air. If involved in a fire phosphine gas, a highly flammable and toxic gas, will evolve. TRIBUTYLPHOSPHINE(998-40-3) is irritating to mucous membranes. | [Reactivity Profile]
Organophosphates, such as TRIBUTYLPHOSPHINE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. | [Air & Water Reactions]
Highly flammable. May ignite on contact with air or moist air. Insoluble in water. | [Health Hazard]
Fire will produce irritating, corrosive and/or toxic gases. Inhalation of decomposition products may cause severe injury or death. Contact with substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution. | [Fire Hazard]
Flammable/combustible material. May ignite on contact with moist air or moisture. May burn rapidly with flare-burning effect. Some react vigorously or explosively on contact with water. Some may decompose explosively when heated or involved in a fire. May re-ignite after fire is extinguished. Runoff may create fire or explosion hazard. Containers may explode when heated. | [Chemical Properties]
Clear liquid | [Uses]
1,4-addition catalyst; used with disulfides for the thioetherification of alcohols; acylation catalyst; used to prepare active esters. | [Uses]
suzuki reaction | [Uses]
Tributylphosphine is usually used as catalyst for Domino reactions of activated conjugated dienes with β,γ-unsaturated-α-ketoesters, [3+2]-Cycloadditions,Umpolung addition reactions,Reductive carbonylation, Allylation reactions.
| [Synthesis Reference(s)]
Tetrahedron Letters, 25, p. 2493, 1984 DOI: 10.1016/S0040-4039(01)81213-2 | [Purification Methods]
Fractionally distil it under reduced pressure in an inert atmosphere (N2) through an 8inch gauze-packed column (b 110-111o/10mm) and redistil it in a vacuum, then seal it in thin glass ampoules. It is easily oxidised by air to tri-n-butylphosphine oxide, b 293-296o/745mm. It has a characteristic odour, it is soluble in EtOH, Et2O, and *C6H6 but is insoluble in H2O and less easily oxidised by air than the lower molecular weight phosphines. It forms complexes, e.g. with CS2 (1:1) m 65.5o (from EtOH). [Davies & Jones J Chem Soc 33 1929, Chernick & Skinner J Chem Soc 1401 1956, Beilstein 4 IV 3436.] |
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