54-92-2
中文名称
异丙烟肼
英文名称
iproniazid
CAS
54-92-2
分子式
C9H13N3O
分子量
179.222
MOL 文件
54-92-2.mol
更新日期
2024/05/07 10:15:38
54-92-2 结构式
基本信息
中文别名
异丙烟肼异烟酰异丙肼
N'-异丙基异烟肼
英文别名
IPRAZIDiproniazid
N'-Isopropylpyridine-4-Carbohydrazide
N'-propan-2-ylpyridine-4-carbohydrazide
物理化学性质
熔点112.5-113.5°
沸点311.75°C (rough estimate)
密度1.1305 (rough estimate)
折射率1.5100 (estimate)
储存条件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度可溶于DMSO（少许）、甲醇（少许）
酸度系数(pKa)11.28±0.23(Predicted)
形态固体
颜色浅米色
CAS 数据库54-92-2
安全数据
警示词警告
危险性描述H302
海关编码2933399990
毒性An isopropyl derivative of isoniazid that was
found to have mood-elevating effects in tuberculosis patients.
It was later found to be a monoamine oxidase (MAO) inhibitor
and, although not currently approved for clinical use as an
antidepressant due to its propensity to cause liver damage it
led to the development of other MAO inhibitors currently in
use. In addition to hepatotoxic effects, iproniazid is a hypotensive
agent and can cause potentially hazardous reactions with
other drugs and amine-rich foods.