12(S)-HETE
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- CAS号:
- 54397-83-0
- 英文名:
- 12(S)-HETE
- 英文别名:
- 12(S)-HETE;(s)-12-hete;12(S) HETE,12(S)HETE;12(S)-HETE MaxSpecStandard;12(S)-HETE Lipid Maps MS Standard;(S)-12-Hydroxyeicosatetraenoic acid;12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid;12(S)-hydroxy-(5Z,8Z,10E,14Z)-*eicosatetraenoic A;12(S)-HYDROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;12(S)-HYDROXY-(5Z,8Z,10E,14Z)-EICOSATETRAENOIC ACID
- 中文名:
- 12(S)-HETE
- 中文别名:
- 12(S)-羟基-(5Z,8Z,10E,14Z)-二十碳四烯酸
- CBNumber:
- CB0483829
- 分子式:
- C20H32O3
- 分子量:
- 320.47
- MOL File:
- 54397-83-0.mol
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12(S)-HETE化学性质
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沸点:
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487.7±45.0 °C(Predicted)
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密度:
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0.984±0.06 g/cm3(Predicted)
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闪点:
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14 °C
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储存条件:
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-20°C
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溶解度:
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0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
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形态:
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Liquid.
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酸度系数(pKa):
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4.75±0.10(Predicted)
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BRN:
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2656104
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12(S)-HETE性质、用途与生产工艺
12（S）-HETE是一种生物活性脂质，参与肿瘤细胞系和动物模型中的血管生成、生长和转移作用。花生四烯酸12脂氧合酶（12LOX）将花生四烯酸转化为12（S）-（HETE）。在包括前列腺癌在内的各种癌症中已经报道了12-Lox表达或活性的改变。所以，抑制12-Lox ，降低12（S）-HETE可以有效抑制肿瘤的生成、生长转移。
12(S)-HETE
上下游产品信息
上游原料
下游产品
54397-83-0, 12(S)-HETE 相关搜索:
- Metabolites & Impurities
- Glycerols
- Fatty Acid Derivatives & Lipids
- Aliphatics
- 抑制剂
- 生化试剂
- BioChemical
- Polyunsaturated
- Omega 6 fatty acids and derivatives
- Lipids
- Unsaturated fatty acids and derivatives
- Fatty Acids
- Biochemicals and Reagents
- 12(S)-羟基-(5Z,8Z,10E,14Z)-二十碳四烯酸
- 54397-83-0
- 12(S) HETE,12(S)HETE
- 5,8,10,14-Eicosatetraenoic acid, 12-hydroxy-, (5Z,8Z,10E,12S,14Z)-
- 12(S)-HETE MaxSpecStandard
- 12(S)-HETE;12(S)-HYDROXY-(5Z,8Z,10E,14Z)-EICOSATETRAENOIC ACID
- (S)-12-Hydroxyeicosatetraenoic acid
- (5Z,8Z,10E,12S,14Z)-12-Hydroxyicosa-5,8,10,14-tetraenoic acid
- (5Z,8Z,10E,12S,14Z)-12-Hydroxy-5,8,10,14-icosatetraenoic acid
- (s)-12-hete
- 12(S)-HYDROXY-(5Z,8Z,10E,14Z)-*EICOSATET RAENOIC ACI
- 12(S)-hydroxy-(5Z,8Z,10E,14Z)-*eicosatetraenoic A
- (12S,5Z,8Z,10E,14Z)-12-Hydroxyeicosatetraenoic acid
- 12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid
- [S-(E,Z,Z,Z)]-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
- 12(S)-HETE Lipid Maps MS Standard
- 12(S)-HYDROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID
- 12(S)-HETE
- 12(S)-HYDROXY-(5Z,8Z,10E,14Z)-EICOSATETRAENOIC ACID