(R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸
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- CAS号:
- 77521-29-0
- 英文名:
- (RS)-AMPA
- 英文别名:
- AMPA;C13672;AMPA HBR;(RS)-AMPA;(RS)-AMPA hydrobromi;AMPA (ZWITTERION) POTENT EXCITATORY AMI;5-Methyl-3-hydroxy-α-aminoisoxazole-4-propionic acid;2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID;2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid;(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
- 中文名:
- (R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸
- 中文别名:
- 化合物 T16800;化合物(RS)-AMPA;(RS)-AMPA,AMPA激动剂;(R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸;(R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸
- CBNumber:
- CB0714231
- 分子式:
- C7H10N2O4
- 分子量:
- 186.17
- MOL File:
- 77521-29-0.mol
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(R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸化学性质
(R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸性质、用途与生产工艺
(RS)-AMPA ((±)-AMPA) 是一种谷氨酸类似物，是一种有效的选择性兴奋性神经递质 L-谷氨酸 (L-glutamic acid) 激动剂。(RS)-AMPA 不会干扰海藻酸或 NMDA 受体的结合位点。
(RS)-AMPA (10-3-10-4 M) causes depolarizations of cultured rat spinal and brainstem neurones. The depolarization by (RS)-AMPA is clearly dose-dependent, although there is a great variability of effects between individual neurones. Application of (RS)-AMPA at 10-5 M produces only small depolarizations (3-7 mV), whereas at 10-4 M, the amplitudes of the depolarizations ranged from 4 to 33 mV. (RS)-AMPA also causes an increase of the discharge rate of spontaneously firing neurones or sometimes evoked a short burst of action potentials in silent cells. (RS)-AMPA exerts its depolarizing effects by activating glutamate/quisqualate receptors without affecting NMDA receptors.
(R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸
上下游产品信息
上游原料
下游产品
(R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸
生产厂家
77521-29-0, (R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸 相关搜索:
- Glutamate receptor
- Neurochemicals
- Heterocyclic Compounds
- 合成有机化合物配体
- Modified Amino Acids
- Ligand-Gated Ion Channels
- Ionotropic Glutamate Receptor Modulators
- Ion Channels
- Biochemicals and Reagents
- A - H
- Amino Acids and Peptides
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- (RS)-AMPA,AMPA激动剂
- 化合物(RS)-AMPA
- 化合物 T16800
- (R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸
- (R,S)-Α-氨基-3-羟基-5-甲基-4-异恶唑丙酸
- 77521-29-0
- glutamate,iGluR,neurotransmitter,kainic,Ionotropic glutamate receptors,(RS)-AMPA,NMDA,Inhibitor,CNS,(RS) AMPA,L-glutamic,inhibit,interneurones,Depolarizations,motoneurones,(RS)AMPA
- (RS)-AMPA hydrobromi
- 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-
- AMPA
- 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid
- C13672
- (S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid
- α-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
- 5-Methyl-3-hydroxy-α-aminoisoxazole-4-propionic acid
- 2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid
- (RS)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazol-propionic acid hydrobromide
- (r,s)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, Hydrobromide
- (±)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrobromide
- AMPA HBR
- AMPA (ZWITTERION) POTENT EXCITATORY AMI
- (+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
- (R,S)-2-AMINO-3-(3-HYDROXY-5-METHYL-4-ISOXAZOLYL)PROPIONIC ACID
- (RS)-ALFA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
- (RS)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
- (R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
- (RS)-AMPA
- 2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID