ChemicalBook >> CAS DataBase List >>(RS)-AMPA
(RS)-AMPA
- CAS No.
- 77521-29-0
- Chemical Name:
- (RS)-AMPA
- Synonyms
- AMPA;C13672;AMPA HBR;(RS)-AMPA;(RS)-AMPA hydrobromi;AMPA (ZWITTERION) POTENT EXCITATORY AMI;5-Methyl-3-hydroxy-α-aminoisoxazole-4-propionic acid;2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID;2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid;(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
- CBNumber:
- CB0714231
- Molecular Formula:
- C7H10N2O4
- Molecular Weight:
- 186.17
- MDL Number:
- MFCD00069214
- MOL File:
- 77521-29-0.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 240 °C |
|---|---|
| Density | 1.386±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | H2O: 1.2 mg/mL |
| form | solid |
| pka | 2.15±0.10(Predicted) |
| color | white |
| Water Solubility | Soluble in water (10mM, gentle warming) |
| Stability | Hygroscopic |
| CAS DataBase Reference | 77521-29-0 |
| FDA UNII | J090588E6X |
| EPA Substance Registry System | .alpha.-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (77521-29-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
(RS)-AMPA price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14571 | (R,S)-AMPA ≥99% | 77521-29-0 | 10mg | $119 | 2021-12-16 | Buy |
| Cayman Chemical | 14571 | (R,S)-AMPA ≥99% | 77521-29-0 | 50mg | $536 | 2021-12-16 | Buy |
| TRC | A611500 | (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicAcid | 77521-29-0 | 50mg | $430 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AAA0017655 | (R,S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID 95.00% | 77521-29-0 | 5MG | $498.52 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 6594 | (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hydrobromide | 77521-29-0 | 10mg | $840 | 2021-12-16 | Buy |
(RS)-AMPA Chemical Properties,Uses,Production
Chemical Properties
White-to-Off White Powder
Uses
A potent and selective agonist of the excitatory neurotransmitter L-glutamic Acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists
Uses
AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission. Because AMPA does not interfere with binding sites for kainic acid or NMDA , it can be used to distinguish AMPA receptor-specific activity that contributes to a neuronal response. (R,S)-AMPA contains an equal mixture of the active (S)-enantiomer and the inactive (R)-enantiomer.
Definition
ChEBI: (S)-AMPA is a non-proteinogenic alpha-amino acid.
Biological Activity
More water soluble hydrobromide salt of ( RS )-AMPA ((RS)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid ).
storage
Room temperature
(RS)-AMPA Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 44)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 18521735133 18521732826; | market@aladdin-e.com | China | 25014 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55954 | 58 |
| Shanghai zhigan biotechnology co., LTD | zhiqianbio@126.com | China | 19785 | 58 |
77521-29-0((RS)-AMPA)Related Search:
2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID
(RS)-AMPA
(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
(RS)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
(RS)-ALFA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
(R,S)-2-AMINO-3-(3-HYDROXY-5-METHYL-4-ISOXAZOLYL)PROPIONIC ACID
(+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
AMPA (ZWITTERION) POTENT EXCITATORY AMI
AMPA HBR
(±)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrobromide
(r,s)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, Hydrobromide
(RS)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazol-propionic acid hydrobromide
2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propanoic acid
5-Methyl-3-hydroxy-α-aminoisoxazole-4-propionic acid
α-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
(S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid
C13672
2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid
AMPA
4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-
(RS)-AMPA hydrobromi
glutamate,iGluR,neurotransmitter,kainic,Ionotropic glutamate receptors,(RS)-AMPA,NMDA,Inhibitor,CNS,(RS) AMPA,L-glutamic,inhibit,interneurones,Depolarizations,motoneurones,(RS)AMPA
77521-29-0
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Amino Acids and Peptides
A - H
Biochemicals and Reagents
Ion Channels
Ionotropic Glutamate Receptor Modulators
Ligand-Gated Ion Channels
Modified Amino Acids
Heterocyclic Compounds
Neurochemicals
Glutamate receptor