QX-314
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- CAS号:
- 5369-03-9
- 英文名:
- QX 314 chloride
- 英文别名:
- QX314.Cl;QX 314 CHLORIDE;N-Ethyllidocaine chloride;Lidocaine N-ethyl chloride;QX-314;QX314;N-ETHYLLIDOCAINE CHLORIDE;[2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium chloride;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM CHLORIDE;[2-(2,6-dimethylanilino)-2-keto-ethyl]-triethyl-ammonium chloride;[2-[(2,6-dimethylphenyl)amino]-2-oxo-ethyl]-triethyl-azanium chloride;2-(2,6-Dimethylphenylamino)-N,N,N-triethyl-2-oxoethanaminium chloride
- 中文名:
- QX-314
- 中文别名:
- 化合物QX-314 CHLORIDE;QX-314氯化物(N-乙基乙卡因氯化物)
- CBNumber:
- CB1191994
- 分子式:
- C16H27ClN2O
- 分子量:
- 298.85
- MOL File:
- 5369-03-9.mol
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QX-314化学性质
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熔点:
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209-211 °C
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储存条件:
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Room temp
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溶解度:
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insoluble in EtOH; ≥14.95 mg/mL in DMSO with gentle warming; ≥22.3 mg/mL in H2O
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形态:
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solid
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颜色:
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White
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水溶解性:
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Soluble in water (100mM)
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QX-314性质、用途与生产工艺
QX-314 chloride 是一种膜不渗透的钠离子通道永久性电荷阻滞剂。
QX-314 chloride exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels (TRPV1) in vitro.
QX-314 chloride (1–60 mM) directly activates TRPV1 in a concentration-dependent manner.
QX-314 chloride (10 mM) inhibits calcium currents in hippocampal CA1 pyramidal neurons intracellular, and the low-threshold (T-type) Ca
2+
currents are on average < 45% of control amplitude.
QX-314
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-108505 | QX-314
QX-314 chloride | 5369-03-9 | 5mg | 196元 |
| 2024/04/30 | HY-108505 | QX-314
QX-314 chloride | 5369-03-9 | 10mg | 315元 |
5369-03-9, QX-314 相关搜索:
- Ion Channels
- Sodium Channel Modulators
- Voltage-gated Ion Channels
- Ion Channels
- Monovalent Ion Channels
- Other Sodium Channel Modulators
- BioChemical
- Cell Biology
- Cell Signaling and Neuroscience
- C16H27N2OCl
- 5369-3-9
- QX-314氯化物(N-乙基乙卡因氯化物)
- 化合物QX-314 CHLORIDE
- 5369-03-9
- Inhibitor,calcium,Sodium Channel,QX314 chloride,channel,Na channels,QX314,sodium,Na+ channels,QX-314,inhibit,QX 314 chloride,QX 314
- QX-314;QX314;N-ETHYLLIDOCAINE CHLORIDE
- N-Ethyllidocaine chloride
- Lidocaine N-ethyl chloride
- [2-[(2,6-dimethylphenyl)amino]-2-oxo-ethyl]-triethyl-azanium chloride
- [2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium chloride
- [2-(2,6-dimethylanilino)-2-keto-ethyl]-triethyl-ammonium chloride
- 2-(2,6-Dimethylphenylamino)-N,N,N-triethyl-2-oxoethanaminium chloride
- QX314.Cl
- N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM CHLORIDE
- QX 314 CHLORIDE