马来酸乙巯拉嗪
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- CAS号:
- 1179-69-7
- 英文名:
- THIETHYLPERAZINE MALEATE (200 MG)
- 英文别名:
- gs-95;torecan;tresten;toresten;nsc-130044;torecanmaleate;2-butenedioate;torecandimaleate;torecanbimaleate;(z)-10h-phenothiazin
- 中文名:
- 马来酸乙巯拉嗪
- 中文别名:
- 马来酸乙巯拉嗪;二马来酸硫乙基哌嗪;化合物 T17072;马来酸乙巯拉嗪 USP标准品
- CBNumber:
- CB1501423
- 分子式:
- C4H2O4-2
- 分子量:
- 114.05628
- MOL File:
- 1179-69-7.mol
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马来酸乙巯拉嗪化学性质
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熔点:
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>146oC (dec.)
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储存条件:
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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溶解度:
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DMSO (Slightly), Methanol (Slightly, Heated)
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形态:
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Solid
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颜色:
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Off-White to Pale Yellow
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稳定性:
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Hygroscopic
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马来酸乙巯拉嗪性质、用途与生产工艺
Thiethylperazine dimaleate 是一种吩噻嗪衍生物，也是一种口服活性多巴胺 D2 受体和组胺 H1 受体拮抗剂。Thiethylperazine dimaleate 也是一种选择性的 ABCC1 激活剂，可减少小鼠中的淀粉样 β (Aβ) 负荷。Thiethylperazine dimaleate 具有止吐，抗精神病和抗菌作用。
Dopamine D2-receptor
Histamine H1-receptor
ABCC1
Enterococcus faecalis
Thiethylperazine could enhance the antibiotic (Vancomycin) activity at a concentration as low as 2 μg/mL. Thiethylperazine inhibits Vancomycin-sensitive
E. faecalis
ATCC 29212, Vancomycin-resistant
E. faecalis
ATCC 51299 and vancomycin-resistant
E. faecalis
(VREF) isolates with MIC values of 8 μg/mL, 16 μg/mL and 8 μg/mL, respectively.
Thiethylperazine (3 mg/kg; intramuscular injection; twice daily; for 30 days; young APP/PS1 mice) treatment significantly reduces Aβ42 levels in APP/PS1 mice.
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Animal Model:
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Young Aβ precursor protein (APPswe) and mutant presenilin-1 (PS1) (
APP/PS1
) mice
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Dosage:
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3 mg/kg
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Administration:
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Intramuscular injection; twice daily; for 30 days
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Result:
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Significantly reduced Aβ42 levels in APP/PS1 mice.
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马来酸乙巯拉嗪
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-B1794A | 马来酸乙巯拉嗪
Thiethylperazine dimaleate | 1179-69-7 | 5 mg | 1000元 |
| 2024/04/30 | HY-B1794A | 马来酸乙巯拉嗪
Thiethylperazine dimaleate | 1179-69-7 | 10 mg | 1500元 |
1179-69-7, 马来酸乙巯拉嗪 相关搜索:
- C22H29N3S2C4H4O42
- 化合物 T17072
- 二马来酸硫乙基哌嗪
- 马来酸乙巯拉嗪 USP标准品
- 马来酸乙巯拉嗪
- 1179-69-7
- hiethylperazinemaleate
- Thiethylperazine Maleate (1658008)
- Thiethylperazine MaleateQ: What is
Thiethylperazine Maleate Q: What is the CAS Number of
Thiethylperazine Maleate Q: What is the storage condition of
Thiethylperazine Maleate Q: What are the applications of
Thiethylperazine Maleate
- 3-ethylmercapto-10-(1’-methylpiperazinyl-4’-propyl)phenothiazinedimaleate
- 2-ethylmercapto-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazinedimaleate
- 2-butenedioate
- 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1:2)
- 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1
- 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinemaleate(1:2
- 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinedimaleate
- 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazindimaleat
- (z)-10h-phenothiazin
- THIETHYLPERAZINE MALEATE (200 MG)
- thiethylperazine di(hydrogen maleate)
- tresten
- toresten
- torecanmaleate
- torecandimaleate
- torecanbimaleate
- torecan
- thiethylperazinemaleate
- thiethylperazinedimaleate
- nsc-130044
- gs-95