丁萘夫汀
|
|
- CAS号:
- 32421-46-8
- 英文名:
- bunaftine
- 英文别名:
- Meregon;bunaftine;Bunaftide;Bunaphtine;Bunaphtide;N-Butyl-N-[2-(diethylamino)ethyl]-1-naphthalenecarboxamide;N-butyl-N-[2-(diethylamino)ethyl]naphthalene-1-carboxamide;1-Naphthalenecarboxamide, N-butyl-N-[2-(diethylamino)ethyl]-
- 中文名:
- 丁萘夫汀
- 中文别名:
- 丁萘夫汀;化合物 T10634
- CBNumber:
- CB6926177
- 分子式:
- C21H30N2O
- 分子量:
- 326.48
- MOL File:
- 32421-46-8.mol
|
|
|
丁萘夫汀化学性质
-
沸点:
-
bp0.1 178°
-
|
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
丁萘夫汀性质、用途与生产工艺
Bunaftide (Bunaftine; Bunaphtide; Meregon) 是一种抗心律失常剂。
At concentrations of 0.5-2.0 mM, Bunaftide causes contraction and rounding of the cells with loss of microvilli-like processes. Aggregates of dense, partly granular, partly fibrillar material form in the cytoplasm and the rough endoplasmic reticulum became vesiculated. Bundles of actin filaments are disrupted, forming rings, coils, and granules. 0.4 mM Bunaftide increases and 0.8-1.0 mM markedly decreases the percentage of mitotic cells, without accumulation of cells in any particular stage of mitosis. The drug may arrest the cell cycle at some point before mitosis; it may have a critical concentration above which the arrest becomes permanent. Bunaftide at 1, 5 and 10 mg/L produces a concentration-dependent depression of the maximum rate of rise of the action potential in guinea pig papillary muscle preparations without affecting the resting membrane potential and the action potential amplitude. The action potential duration (APD50, APD90) is significantly prolonged by the treatment with 1 and 5 mg/L Bunaftide, while it is not changed by the treatment with 10 mg/L.
丁萘夫汀
上下游产品信息
上游原料
下游产品
32421-46-8, 丁萘夫汀 相关搜索:
- 化合物 T10634
- 丁萘夫汀
- 32421-46-8
- 1-Naphthalenecarboxamide, N-butyl-N-[2-(diethylamino)ethyl]-
- N-butyl-N-[2-(diethylamino)ethyl]naphthalene-1-carboxamide
- bunaftine
- Bunaftide
- N-Butyl-N-[2-(diethylamino)ethyl]-1-naphthalenecarboxamide
- Meregon
- Bunaphtine
- Bunaphtide