辛伐他汀钠盐
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- CAS号:
- 101314-97-0
- 英文名:
- SIMVASTATIN, SODIUM SALT
- 英文别名:
- Simvastati;Simvasatin Ep Imp A;SIMVASTATIN, SODIUM SALT;FYSMQCWXGBXWLB-VMCZNHHFSA-M;Simvastatin Impurity 1（EP-A）;Simvastatin Acid Sodium Salt;Simvastatin hydroxy acid sodium;Simvastatin Impurity as Sodium Salt;SimvastatinEPImpurityA-d6SodiumSalt;SIMVASTATIN HYDROXY ACID SODIUM SALT
- 中文名:
- 辛伐他汀钠盐
- 中文别名:
- 辛伐他汀钠;辛伐他汀钠盐;辛伐他汀酸钠;辛伐他汀杂质A;辛伐他汀羟基酸钠;羟基辛伐他汀酸钠;辛伐他汀羟基酸钠盐;辛伐他汀EP杂质钠盐;辛伐他汀羟酸(钠盐);辛伐他汀EP杂质A钠盐
- CBNumber:
- CB8320771
- 分子式:
- C25H41NaO6
- 分子量:
- 460.59
- MOL File:
- Mol file
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辛伐他汀钠盐化学性质
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熔点:
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>122°C (dec.)
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储存条件:
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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溶解度:
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DMSO (Slightly), Methanol (Slightly), Water (Slightly)
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形态:
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White powder solid.
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颜色:
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White to Pale Beige
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稳定性:
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Hygroscopic
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辛伐他汀钠盐性质、用途与生产工艺
Simvastatin hydroxy acid sodium (Tenivastatin sodium; Simvastatin Impurity A sodium) 是辛伐他汀 (HY-17502) 活性水解代谢物。Simvastatin 是一种竞争性的 HMG-CoA 还原酶抑制剂， Ki 值为 0.2 nM。
Simvastatin sodium shows a inhibition of HMG-CoA reductase in human lymphoblasts and SV40 transformed MRCS fibroblasts.Simvastatin sodium (100 μM) inhibits the Na
+
/H
+
antiport activity leading to a fall of intracellular pH and to a reduced cell proliferation.And the inhibitory effect is prevented by mevalonate but not dolichol or squalene.
Simvastatin sodium (oral administration; 8 mg/kg; 18 days) reduces plasma cholesterol levels 33%, simvastatin can be used in combination with ezetimibe to treat dyslipidemia.
辛伐他汀钠盐
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-115292 | Simvastatin hydroxy acid sodium | | 1 mg | 1580元 |
辛伐他汀钠盐
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辛伐他汀钠盐国内生产厂家
101314-97-0, 辛伐他汀钠盐 相关搜索:
- 杂质对照品
- 168- 辛伐他汀
- C25H39O6Na
- 12009-77-6
- 辛伐他汀杂质1 钠盐(辛伐他汀EP杂质A钠盐)
- 辛伐他汀羟酸(钠盐)
- 辛伐他汀EP杂质A钠盐
- 辛伐他汀杂质A (EP)
- 辛伐他汀酸钠
- 辛伐他汀羟基酸钠
- 辛伐他汀钠
- 辛伐他汀相关化合物A(USP)
- 辛伐他汀EP杂质钠盐
- 辛伐他汀杂质01(NA)
- 辛伐他汀杂质A(EP) 标准品
- 辛伐他汀杂质A
- 辛伐他汀羟基酸钠盐
- 辛伐他汀钠盐
- 辛伐他汀羟基酸钠盐-D6
- 羟基辛伐他汀酸钠
- 101314-97-0
- 1-Naphthaleneheptanoic acid,8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-b,d-dihydroxy-2,6-dimethyl-, monosodium salt, [1S-[1a(bS*,dS*),2a,6b,8b,8aa]]-
- Simvastatin Impurity 1 Sodium Salt(Simvastatin EP Impurity A Sodium Salt)
- Simvastatin EP Impurity A as Sodium Salt
- Simvastatin Impurity A as Sodium Salt
- SimvastatinEPImpurityA-d6SodiumSalt
- Simvastatin Impurity A sodium salt（EP）
- Simvastatin Acid Sodium Salt
- Simvastatin EP Impurity AQ: What is
Simvastatin EP Impurity A Q: What is the CAS Number of
Simvastatin EP Impurity A Q: What is the storage condition of
Simvastatin EP Impurity A Q: What are the applications of
Simvastatin EP Impurity A
- Simvastatin hydroxyl acid D6 Sodium salt
- Simvasatin EP Impurity A/ Simvasatin Related Compound A (Simvastatin Sodium/ Tenivastatin Sodium)
- Simvasatin Ep Imp A
- Simvastatin hydroxy acid sodium
- Simvastatin Impurity 1（EP-A）
- Simvastatin Impurity 1(Simvastatin EP Impurity A)
- Sodium (3R,5R)-7-{(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-1-naphthalenyl}-3,5-dihydroxyheptanoate
- FYSMQCWXGBXWLB-VMCZNHHFSA-M
- Simvastatin EP Impurity A Sodium Salt
- Simvastatin hydroxyl acid sodium salt-d6
- sodium,(3R,5S)-7-[(1R,2R,6S,8S)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
- SiMvastatin IMp. A (EP) as SodiuM Salt
- Simvastati
- Simvastatin Impurity as Sodium Salt
- IMp. A (EP) as SodiuM Salt: (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-DiMethylbutanoyl)oxy]-2,6-diMethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid SodiuM Salt (Tenivastatin SodiuM Salt
- SIMVASTATIN, SODIUM SALT
- SIMVASTATIN HYDROXY ACID SODIUM SALT