심바스타틴,나트륨소금
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심바스타틴,나트륨소금 속성
- 녹는점
- >122°C (dec.)
- 저장 조건
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)
- 물리적 상태
- 백색 분말 고체.
- 색상
- 흰색에서 옅은 베이지까지
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
그림문자(GHS): | ||||||||||||||||||||||
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신호 어: | Warning | |||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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심바스타틴,나트륨소금 C화학적 특성, 용도, 생산
개요
Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-κB activation (IC50 = ~13 μM) and potentiates apoptosis in human myeloid leukemia cells. It also inhibits glutathione peroxidase 4 (GPX4) activity, increases malondialdehyde (MDA) levels, and induces ferroptosis in MDA-MB-231 and MCF-7 breast cancer cells. Formulations containing simvastatin have been used in the treatment of dyslipidemias.용도
Simvastatin Hydroxy Acid Sodium Salt is a metabolite of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.심바스타틴,나트륨소금 준비 용품 및 원자재
원자재
Lovastatin Triol Acid Sodium Salt
2,2-Dimethylbutyryl chloride
3-[(2,2-디메틸-1-옥소부틸)티오]프로판산메틸에스테르
로바스타틴
준비 용품
심바스타틴,나트륨소금 공급 업체
글로벌( 84)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14336 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9633 | 58 |
sgtlifesciences pvt ltd | +8617013299288 |
dj@sgtlifesciences.com | China | 12382 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 |
overseasales@yongstandards.com | China | 11927 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
Guangzhou PI PI Biotech Inc | +86-020-81716320 +86-13602409664 |
Sales@pipitech.com | China | 3635 | 55 |
심바스타틴,나트륨소금 관련 검색:
로바스타틴
Simvastatin
6'-EXOMETHYLENE SIMVASTATIN
Simvastatin ammonium salt
SiMvastatin Methyl Ester
2′-Ethyl Simvastatin
SiMvastatin 4'-Methyl Ether
Simvastatin Hydroxy Acid Methyl Ester
SiMvastatin Hydroxy Acid Ethyl Ester
ACETYLSIMVASTATIN
MONACOLIN J
Dehydro Simvastatin
SiMvastatinAcetate Ester
Simvastatin Dimer
SiMvastatin EP IMpurity G
Epi Lovastatin
AnhydrosiMvastatin
SiMvastatin EP IMpurity G