Panidazole in concentrations of 0.02-1 mM increases the mutation frequency of
Klebsiella pneumoniae
,
Escherichia coli
K12 and
Citrobacter freundii
to streptomycin resistance, including streptomycin dependence, in Luria and Delbrück's fluctuation test.
In 100 cases of vaginal trichomoniasis treated with panidazole at the dose of 1.0 g per day for seven days in half of the patients and for 10 days in the other half, we obtained 50% and 60% cure rates.