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Metergolin

METERGOLINE Struktur
17692-51-2
CAS-Nr.
17692-51-2
Bezeichnung:
Metergolin
Englisch Name:
METERGOLINE
Synonyma:
mce;ahr3009;Lyserdol;liserdol;metergolin;metergolina;METERGOLINE;methergoline;METERGOLINE, INTERNAL;METERGOLINE USP/EP/BP
CBNumber:
CB1248755
Summenformel:
C25H29N3O2
Molgewicht:
403.52
MOL-Datei:
17692-51-2.mol
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Metergolin Eigenschaften

Schmelzpunkt:
148-150 °C(lit.)
alpha 
D28 -7 ±2°
Siedepunkt:
612.5±55.0 °C(Predicted)
Dichte
1.25±0.1 g/cm3(Predicted)
storage temp. 
−20°C
Löslichkeit
0.1 M HCl: 1.4 mg/mL
pka
12.45±0.46(Predicted)
Aggregatzustand
solid
Farbe
White
Merck 
13,5962
Stabilität:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethaqnol may be stored at -20°C for up to 2 month.
InChIKey
WZHJKEUHNJHDLS-QTGUNEKASA-N
CAS Datenbank
17692-51-2(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher Xn
R-Sätze: 20/21/22
S-Sätze: 36
WGK Germany  3
RTECS-Nr. FA1070000
Toxizität LD50 in mice (mg/kg): 85 i.p., 430 orally; in rats (mg/kg): >800 orally (Beretta)

Metergolin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

White Solid

Verwenden

Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.

Biologische Aktivität

Antagonist at 5-HT 1 /5-HT 2 with activity at 5-HT 1D . Has moderate affinity for 5-HT 6 and high affinity for 5-HT 7 .

Metergolin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Benzylchlorformiat

Downstream Produkte

Metergolin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 87)Lieferanten
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17692-51-2(Metergolin)Verwandte Suche:

Metergolin 3-Phenylpiperidin 1-Methyl-1H-indol-3-ethylamin
  • n-cbz-[(8β)-1,6-dimethylergolin-8-yl]methylamine
  • N-Cbz-[(8β)-1,6-Dimethylergolin-8-yl]methylamine, [(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester
  • [((8beta)-1,6-Dimethylergoline-8-yl)methyl]carbamic acid phenylmethyl ester
  • Lyserdol
  • N-[(1,6-Dimethylergolin-8β-yl)methyl]carbamic acid benzyl ester
  • [(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamicacidphenylmethylester
  • D-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aalpha-indolo[4,3-fg]quinolin-9beta-yl)methyl]carbamic acid benzyl ester
  • liserdol
  • mce
  • metergolin
  • metergolina
  • methergoline
  • n-carboxy-9,10-dihydro-1-methyl-lysergaminbenzylester
  • METERGOLINE 5-HT1/5-HT2 SEROTONIN
  • METERGOLINE, INTERNAL
  • Carbamic acid, (8.beta.)-1,6-dimethylergolin-8-ylmethyl-, phenylmethyl ester
  • N-CBZ-[(8BETA)-1,6-DIMETHYLERGOLIN-8-YL]METHYLAMINE
  • METERGOLINE
  • METERGOLINE PHENYLMETHYL ESTER
  • [((8BETA)-1,6-DIMETHYLERGOLIN-8-YL)METHYL]CARBAMIC ACID PHENYLMETHYL ESTER
  • (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicacibenzylester
  • (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicaciphenylmethylest
  • ((1,6-dimethylergolin-8-beta-yl)methyl)-carbamicacibenzylester
  • 1,6-dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
  • 1-methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
  • 1-methyl-n-carbobenzyloxydihydro-d-lysergamin
  • ahr3009
  • d-8-beta-((carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
  • d-8-beta-((carboxyamino)methyl)-1,6-dimethylergolineibenzylester
  • d-n-carbobenzoxydihydro-1-methyllysergaminei
  • d-n-carboxydihydro-1-methyllysergamineibenzylester
  • Carbamic acid, N-[[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
  • METERGOLINE USP/EP/BP
  • disorder,inhibit,affective,hormone,5-hydroxytryptamine Receptor,Na+ channels,Na channels,Metergoline,regulation,Inhibitor,dysphoric,prolactin,5-HT Receptor,Serotonin Receptor,premenstrual,Sodium Channel,psychoactive,Dopamine Receptor
  • 17692-51-2
  • C25H29N3O2
  • Serotonin receptor
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