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1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Struktur
79183-19-0
CAS-Nr.
79183-19-0
Englisch Name:
1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE
Synonyma:
CS-572;MDK83190;APOPTOSIS ACTIVATOR 2;APOPTOSIS ACTIVATOR II;Apoptosis Activator 2, >=98%;1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE;1-[(3,4-DICHLOROPHENYL)METHYL]-1H-INDOLE-2,3-DIONE;1H-Indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]-;1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE USP/EP/BP;1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indole-2,3-dione
CBNumber:
CB1755989
Summenformel:
C15H9Cl2NO2
Molgewicht:
306.14
MOL-Datei:
79183-19-0.mol
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1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Eigenschaften

Siedepunkt:
470.6±55.0 °C(Predicted)
Dichte
1.494
Flammpunkt:
238.4℃
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
Löslichkeit
Soluble in DMSO
Aggregatzustand
Orange to red solid.
pka
-2.69±0.20(Predicted)
Sensitive 
Light Sensitive

Sicherheit

S-Sätze: 24/25
RIDADR  3077
HS Code  29145090

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.

Biologische Aktivität

Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC 50 = 4-9 μ M for leukaemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC 50 > 40 μ M).

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 125)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32686 60
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29914 58
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22968 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051
 joe@yuhengpharm.com CHINA 21149 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 28608 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10523 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896
 cbc@coresyn.com China 9991 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58

79183-19-0()Verwandte Suche:

Indol 1-Methyl-2,3-dihydroindol-2,3-dion
  • APOPTOSIS ACTIVATOR 2
  • APOPTOSIS ACTIVATOR II
  • 1-[(3,4-DICHLOROPHENYL)METHYL]-1H-INDOLE-2,3-DIONE
  • 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE
  • 1H-Indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]-
  • Apoptosis Activator 2, >=98%
  • Apoptosis Activator 2, 97%, a cytochrome c caspase activator and apoptosis inducer
  • CS-572
  • 1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indole-2,3-dione
  • MDK83190
  • 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE USP/EP/BP
  • 79183-19-0
  • Inhibitors
  • Caspases/Apoptosis
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