Pivalaldehyd Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R37/38:Reizt die Atmungsorgane und die Haut.
R43:Sensibilisierung durch Hautkontakt möglich.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S33:Maßnahmen gegen elektrostatische Aufladungen treffen.
S24:Berührung mit der Haut vermeiden.
Beschreibung
Trimethylacetaldehyde (also known as Pivaldehyde) is the trimethyl
form of acetaldehyde. It is an aldehyde with a sterically bulky R
group, the tertiary-butyl group being attached to the carbonyl,
>C=O. It is a useful reagent in organic synthesis, pharmaceuticals,
agrochemicals and dyestuff. It is useful in streoselective synthesis
application as well as in aldol condensation reactions. As a
derivative of acetaldehyde, trimethyl acetaldehyde can be used for
the production of acetate. It can also be used as the precursor for
manufacturing of pyridine derivatives, pentaerythritol, and
crotonaldehyde.
Chemische Eigenschaften
Clear colorless liquid
Verwenden
Commonly used building block in aldol condensation reactions.
Application
Pivaldehyde is a hazardous by-product released from engine exhaust and is often used as a raw material for organic synthesis or as a reagent in chemical reactions. It can be copolymerised with aldehyde anions, such as acrolein, to prepare unsaturated polyacetals, or a TBPB initiated decarbonylative cascade cyclization of ortho-cyanoarylacrylamides with pivaldehyde leads to tert-butyl containing quinolone-2,4(1H,3H)-diones by formation of both C(sp
3)–C(sp
3) and C(s
p3)–C(sp
2) bonds. As well as probing the absolute rate constants of its autoxidation, etc
[1-3].
Einzelnachweise
Ho, Tse Lok, et al. Pivaldehyde. Fieser and Fieser's Reagents for Organic Synthesis. John Wiley & Sons, Inc. 2006.
https://en.wikipedia.org/wiki/Acetaldehyde#Uses
https://en.wikipedia.org/wiki/Pivaldehyde
https://www.alfa.com/en/catalog/A15013/
Pivalaldehyd Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Clomazone
2,2-Dimethylpropan-1,3-diol
(S)-2-Methylproline
Methylisocyanacetat
N-(Trimethylsilyl)-2,2-dimethylpropane-1-imine
2,2-Dimethylhexan-3-ol
1,9-BIS-BOC-1,5,9-TRIAZANONANE
methyl (2S)-2-amino-3,3-dimethylbutanoate
2,2-DIMETHYL-3-HEXANONE
(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE
Ethyl-4,4-dimethyl-3-oxovalerat
2-AMINO-5-TERT-BUTYL-1,3,4-THIADIAZOLE
2R,5S)-5-benzyl-2-tert-butyl-3-MethyliMidazolidin-4-one