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Poziotinib (HM781-36B)

1092364-38-9

CAS-Nr.: 1092364-38-9

Englisch Name:: Poziotinib (HM781-36B)

Synonyma:: Poziotinib;CS-1788;NOV120101;pozytinib;Pozzi for;HM781-36B);UNII-OEI6OOU6IK;Poziotinib(NOV120101;Poziotinib HM-781368;poziotinib(HM-78136B)

CBNumber:: CB22668103

Summenformel:: C23H21Cl2FN4O3

Molgewicht:: 491.34

MOL-Datei:: 1092364-38-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 201

Poziotinib (HM781-36B) Eigenschaften

Schmelzpunkt:: 187 - 190° C

Siedepunkt:: 629.7±55.0 °C(Predicted)

Dichte: 1.409±0.06 g/cm3(Predicted)

storage temp.: -20°C Freezer, Under inert atmosphere

Löslichkeit: Chloroform (Slightly), DMSO (Slightly, Sonicated)

pka: 5.35±0.30(Predicted)

Aggregatzustand: Solid

Farbe: White to Pale Beige

CAS Datenbank: 1092364-38-9

Sicherheit

Poziotinib (HM781-36B) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Poziotinib is a TKI that covalently and irreversibly inhibits EGFR and HER2, and is unique because of its small terminal group and flexible quinazoline core. Its small size and flexibility allow it to evade the steric hindrance which affects other EGFR TKIs [138].

Verwenden

Poziotinib can be used to inhibit the growth of cancer cells.

Poziotinib (HM781-36B) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

6-Quinazolinol, 4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 1-[4-[[(4-Methylphenyl)sulfonyl]oxy]-1-piperidinyl]-2-propen-1-one 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol 3,4-Dichloro-2-fluoroaniline Acryloylchlorid

Downstream Produkte

Poziotinib (HM781-36B) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 201)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
HangZhou RunYan Pharma Technology Co.,LTD.	+86-88660901 +86-18112526015	sales@runyanpharma.com	China	326	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15956	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
TianYuan Pharmaceutical CO.,LTD	+86-755-23284190 13684996853	sales@tianpharm.com	CHINA	304	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shenzhen Excellent Biotech Co., Ltd.	13480692018	ramyan@ex-biotech.com	CHINA	954	58
Jurong Coupling Biotechnology Co., Ltd.	13656108824	coupling278191416@hotmail.com	CHINA	184	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8348	58

1092364-38-9()Verwandte Suche:

5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyron

1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one
UNII-OEI6OOU6IK
1-(4-((4-((3,4-dichloro-2-fluorophenyl)aMino)-7- Methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one
1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one
poziotinib(HM-78136B)
NOV120101
1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one Poziotinib
HM781-36B)
Poziotinib(NOV120101
CS-1788
HM781-36B; NOV120101; NOV-120101; NOV 120101; POZIOTINIB
Poziotinib (HM781-37B)
2-Propen-1-one, 1-[4-[[4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-
Poziotinib HM-781368
pozytinib
Pozzi for
3-Pyridinecarbonitrile,6-fluoro-9-nitro-
Poziotinib
Poziotinib (HM-781-36)
1092364-38-9
C23H21Cl2FN4O3
Inhibitors
API