N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE

149649-22-9

CAS-Nr.: 149649-22-9

Englisch Name:: N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE

Synonyma:: NAFADOTRIDE;N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE;2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-

CBNumber:: CB5402878

Summenformel:: C22H27N3O2

Molgewicht:: 365.47

MOL-Datei:: 149649-22-9.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 30

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Eigenschaften

Siedepunkt:: 556.6±40.0 °C(Predicted)

Dichte: 1.17±0.1 g/cm3(Predicted)

storage temp.: Desiccate at RT

pka: 12.84±0.46(Predicted)

Sicherheit

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Nafadotride is a highly potent and competitive dopamine D3 receptor (D3R) antagonist.

Definition

ChEBI: A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, prefer ntial dopamine D3 receptor antagonist, centrally active upon systemic administration.

Biologische Aktivität

Highly potent, competitive, preferential dopamine D 3 receptor antagonist. K i values are 0.52, 5, and 269 nM for human cloned D 3 , D 2 and D 4 receptors respectively. Centrally active upon systemic administration.

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
QUALITY CONTROL SOLUTIONS LTD.	13670046396	ORDERS@QCSRM.COM	China	18820	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	5021	58
United States Biological	--	sales@advtechind.com	United States	6106	58

149649-22-9()Verwandte Suche:

m-Formylbenzonitril 1-Naphthonitril 4-Methoxy-1-naphthonitril

NAFADOTRIDE
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE
2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-
149649-22-9
C22H27N3O2