ChemicalBook >> CAS DataBase List >>Fluorescein Sodium Salt
Fluorescein Sodium Salt
- CAS No.
- 518-47-8
- Chemical Name:
- Fluorescein Sodium Salt
- Synonyms
- FLUORESCEIN SODIUM SALT;SODIUM FLUORESCEIN;CI 45350;ACID YELLOW 73;FLUORESCEIN DISODIUM SALT;URANINE;Fluorin;YELLOW 8;Fluorescite;aizenuranine
- CBNumber:
- CB00123344
- Molecular Formula:
- C20H13NaO5
- Molecular Weight:
- 356.31
- MDL Number:
- MFCD00167039
- MOL File:
- 518-47-8.mol
Last updated:2024-05-23 18:06:45
| Melting point | 320 °C |
|---|---|
| Density | 0.579[at 20℃] |
| vapor pressure | 2.133hPa |
| storage temp. | Store at +5°C to +30°C. |
| solubility | H2O: soluble1mg/mL |
| Colour Index | 45350 |
| form | Powder |
| pka | 2.2, 4.4, 6.7(at 25℃) |
| color | Rust-orange |
| Odor | Odorless |
| PH | 8.3 (10g/l, H2O, 20℃) |
| PH Range | Pink uorescence (4.0) to green uorescence (6.0) |
| Water Solubility | 500 g/L (20 ºC) |
| λmax | 491nm, 493.5nm, 490nm |
| Merck | 14,4159 |
| BRN | 3833041 |
| Stability | Stable. |
| Major Application | Nanolithography, nanoparticles, thin films, fuel cells, inks, laser, colored bubbles, cleansing products, identifying leaks in coolant, suntanning agent, hair dyes, cosmetics, dermatology, dental material, diagnosis of diabetic retinopathy, antitumor agent |
| InChIKey | NJDNXYGOVLYJHP-UHFFFAOYSA-L |
| LogP | 0.34 |
| FDA 21 CFR | 74.1708; 74.2708; 74.3708; 82.1708 |
| CAS DataBase Reference | 518-47-8(CAS DataBase Reference) |
| EWG's Food Scores | 1-3 |
| FDA UNII | 93X55PE38X |
| NCI Drug Dictionary | Fluorescite |
| EPA Substance Registry System | Fluorescein, disodium salt (518-47-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36-36/37/38 | |||||||||
| Safety Statements | 22-24/25-37/39-26-36/37/39-27 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | LM5425000 | |||||||||
| F | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 32041200 | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 4738, 6721 orally (Yankel, Loux) | |||||||||
| NFPA 704 |
|
Fluorescein Sodium Salt price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 46970 | Fluorescein sodium salt p.a., for source staining | 518-47-8 | 100g | $47.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 46960 | Fluorescein sodium salt BioReagent, suitable for fluorescence | 518-47-8 | 25g | $18.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 46970 | Fluorescein sodium salt p.a., for source staining | 518-47-8 | 500g | $167 | 2024-03-01 | Buy |
| Sigma-Aldrich | 46960 | Fluorescein sodium salt BioReagent, suitable for fluorescence | 518-47-8 | 100g | $47.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 46960 | Fluorescein sodium salt BioReagent, suitable for fluorescence | 518-47-8 | 500g | $148 | 2024-03-01 | Buy |
Fluorescein Sodium Salt Chemical Properties,Uses,Production
Description
Fluorescein sodium salt is a disodium salt of fluorescein and a noted pH sensitive fluorophore. It has been utilized in studies as a drug model, as a penetrating dye and also as a fluorescein tracer.
Chemical Properties
Fluorescein sodium is a sodium salt and an organic fluorescent dye with peak excitation at 494 nm and peak emission at 512 nm. It has been safely used in humans for many years, predominantly in ophthalmology for retinal angiography, and the cost of fluorescein sodium is relatively low when compared with the cost of other agents such as 5-ALA.
Uses
Fluorescein is a xanthene dye and is a common labeling agent in biology：
It has been used as a test molecule to study blood barrier penetration.
Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.
Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models.
The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.
Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).
Fluorescein Sodium Salt Preparation Products And Raw materials
Global( 613)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenyang Simchoice Chemical Co.,Ltd | +86-024-23769576 +86-15040101888 | sales@simchoicechem.com | China | 255 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12470 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 19368 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 2999 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15954 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9340 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
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View Lastest Price from Fluorescein Sodium Salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-30 | Fluorescein Sodium
518-47-8
|
25KG | 99% | 1000kgs per month | Shenyang Simchoice Chemical Co.,Ltd | ||
 |
2021-01-01 | Fluorescein Sodium Salt
518-47-8
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Guanlang Biotechnology Co., Ltd. |
-
- Fluorescein Sodium
518-47-8
- 99%
- Shenyang Simchoice Chemical Co.,Ltd
-
- Fluorescein Sodium Salt
518-47-8
- US $1.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
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