Betanidine
- CAS No.
- 55-73-2
- Chemical Name:
- Betanidine
- Synonyms
- BETANIDIN;Betanidine;Bethanidine;Betanidine USP/EP/BP;1-Benzyl-2,3-dimethylguanidine;2-benzyl-1,3-diMethylguanidine;N,N'-Dimethyl-N''-(phenylmethyl)guanidine;Guanidine, N,N''-dimethyl-N'-(phenylmethyl)-
- CBNumber:
- CB11116819
- Molecular Formula:
- C10H15N3
- Molecular Weight:
- 177.25
- MDL Number:
- MOL File:
- 55-73-2.mol
- MSDS File:
- SDS
Melting point | 195-197° |
---|---|
Boiling point | 299.18°C (rough estimate) |
Density | 0.9826 (rough estimate) |
refractive index | 1.4800 (estimate) |
pka | pKa 10.6 (Uncertain) |
FDA UNII | W8S3YM7AUU |
ATC code | C02CC01 |
Betanidine Chemical Properties,Uses,Production
Originator
Bendogen,Lagap Pharmaceuticals SA
Uses
Betanidine is a betacyanin and an aglycone of the beet dye betanin.
Definition
ChEBI: Bethanidine is a member of guanidines. It has a role as an adrenergic antagonist and an antihypertensive agent.
Manufacturing Process
A mixture of 2-bromobenzylamine (12.5 g) and S-methylthiouronium sulfate (10 g) in water (20 ml) was heated for 1.5 hours on a steam bath in a hood, during which methylmercaptan escaped (as evidenced by a foul odour). The reaction mixture was then cooled and diluted with ethanol (100 ml). A colourless solid of 2-bromobenzylguanidine sulfate was separeted, and washed with ethanol. This solid melted at 230-232°C; it was recrystallized from water and then melted at 247-248°C. By action of a basic agent the salt obtained may be converted into free base.
Therapeutic Function
Antihypertensive
Betanidine Preparation Products And Raw materials
Betanidine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
Wuhan Magic Biological Technology Co., Ltd. | 18872289958、027-52304252、3400508168 | 3400508168@qq.com | China | 1910 | 55 |
Supplier | Advantage |
---|---|
Shaanxi Dideu Medichem Co. Ltd | 58 |
Wuhan Magic Biological Technology Co., Ltd. | 55 |
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