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ChemicalBook >> CAS DataBase List >>1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Structure
1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL structure
CAS No.
75144-12-6
Chemical Name:
1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL
Synonyms
Antitrypanosomal agent 1;1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one;1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL;1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanonehydrochloride;1-Propanone1-(34-dichlorophenyl)-3-(dimethylamino)-hydrochloride;1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride;Antitrypanosomal agent-1,Antitrypanosomal agent 1,T.brucei,trypanothione,inhibit,glutathione,Antitrypanosomal agent1,Inhibitor,reductase,Parasite,anti-trypanosomal
CBNumber:
CB11519588
Molecular Formula:
C11H14Cl3NO
Molecular Weight:
282.59
MDL Number:
MFCD01220371
MOL File:
75144-12-6.mol
Last updated:2023-05-18 11:31:13
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1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Properties

Melting point 186 - 188°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White
Water Solubility Water: 10 mg/mL (35.39 mM)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D435873 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanoneHydrochloride 75144-12-6 50mg $45 2021-12-16 Buy
ChemScene CS-0045380 Antitrypanosomalagent1 75144-12-6 1g $85 2021-12-16 Buy
AK Scientific 1400AL 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanoneHCl 75144-12-6 1g $151 2021-12-16 Buy
ChemScene CS-0045380 Antitrypanosomalagent1 75144-12-6 5g $276 2021-12-16 Buy
American Custom Chemicals Corporation HCH0063405 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HYDROCHLORIDE 95.00% 75144-12-6 1G $713.1 2021-12-16 Buy
Product number Packaging Price Buy
D435873 50mg $45 Buy
CS-0045380 1g $85 Buy
1400AL 1g $151 Buy
CS-0045380 5g $276 Buy
HCH0063405 1G $713.1 Buy

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Chemical Properties,Uses,Production

Biological Activity

Antitrypanosomal agent 1 is a potent and selective inhibitor of trypanothione reductase with IC50 of 3.3 μM. It inhibits glutathione reductase with IC50 of 64.8 μM; inhibits Trypanosoma brucei with EC50 of 1 μM. It has antitrypanosomal activity.

in vitro

Antitrypanosomal agent 1 (compound 8a) has an selectivity for TR (GR IC50/TR IC50) of 20.

target

IC50: 3.3 μM (trypanothione reductase) and 64.8 μM (glutathione reductase)
EC50: 1 μM ( T. brucei )

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Preparation Products And Raw materials

Raw materials

Preparation Products

1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL Suppliers

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuxi Rejoys chemical Technology Co., Ltd. 		0510-86103381 sales@rejoyschem.com CHINA 976 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 50000 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501 product@acmec-e.com China 33350 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
TargetMol Chemicals Inc. 		58
Wuxi Rejoys chemical Technology Co., Ltd. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
LEAP CHEM CO., LTD. 		58
GIHI CHEMICALS CO.,LIMITED 		58
LEAPCHEM CO., LTD. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76

75144-12-6(1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL)Related Search:

1-(4-CHLOROPHENYL)-3-(DIMETHYLAMINO)PROPAN-1-ONE HYDROCHLORIDE 3',4'-DICHLOROPROPIOPHENONE 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL
1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL 1-(3,4-Dichlorophenyl)-3-dimethylamino-1-propanonehydrochloride 1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochloride Antitrypanosomal agent 1 1-Propanone1-(34-dichlorophenyl)-3-(dimethylamino)-hydrochloride 1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-one Antitrypanosomal agent-1,Antitrypanosomal agent 1,T.brucei,trypanothione,inhibit,glutathione,Antitrypanosomal agent1,Inhibitor,reductase,Parasite,anti-trypanosomal 75144-12-6