LEUKOTRIENE D4
- CAS No.
- 73836-78-9
- Chemical Name:
- LEUKOTRIENE D4
- Synonyms
- LTD4;leukotriened;LEUKOTRIENE D4;leukotriened(sub4);LTD4 (Leukotriene D4);Leukotriene D4 (LTD4);(r-(r*,s*-(e,e,z,z)))-inyl);YEESKJGWJFYOOK-IJHYULJSSA-N;Leukotriene D4 MaxSpecStandard;LEUKOTRIENE D4 (ETHANOL SOLUTION)
- CBNumber:
- CB1283439
- Molecular Formula:
- C25H40N2O6S
- Molecular Weight:
- 496.66
- MDL Number:
- MFCD00036839
- MOL File:
- 73836-78-9.mol
- MSDS File:
- SDS
| Boiling point | 785.8±60.0 °C(Predicted) |
|---|---|
| Density | 1.162±0.06 g/cm3(Predicted) |
| Flash point | 9℃ |
| storage temp. | -70°C |
| solubility | A solution in ethanol |
| form | Liquid. |
| pka | 3.03±0.10(Predicted) |
| FDA UNII | 5FNY4416UE |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H301+H311+H331-H370 |
| Precautionary statements | P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN 1230 3/PG 2 |
| WGK Germany | 3 |
LEUKOTRIENE D4 price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L5011 | Leukotriene D4 ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97% | 73836-78-9 | 10μg | $317 | 2024-03-01 | Buy |
| Sigma-Aldrich | L5011 | Leukotriene D4 ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97% | 73836-78-9 | 25μg | $629 | 2024-03-01 | Buy |
| Sigma-Aldrich | L5011 | Leukotriene D4 ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97% | 73836-78-9 | 50μg | $950 | 2024-03-01 | Buy |
| Sigma-Aldrich | L5011 | Leukotriene D4 ~50?μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97% | 73836-78-9 | 250μg | $2130 | 2022-05-15 | Buy |
| Cayman Chemical | 20310 | Leukotriene D4 ≥97% | 73836-78-9 | 25μg | $144 | 2024-03-01 | Buy |
LEUKOTRIENE D4 Chemical Properties,Uses,Production
Description
Leukotriene D4 (LTD4) is an active metabolite of LTC4 (Item Nos. 20210 | 10007241) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by γ-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.
Uses
LTD4 (Leukotriene D4) is a member of the leukotriene family shown to be a potent contractor of smooth muscle.
Definition
ChEBI: A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and a L-cysteinylglycinyl group at position 6 (6R).
Biochem/physiol Actions
Slow reacting substance of anaphylaxis (SRS-A). Potent bronchoconstrictor and mediator of asthmatic and inflammatory processes. Increases cytosolic free Ca2+ in epithelial cells.
LEUKOTRIENE D4 Preparation Products And Raw materials
Raw materials
Preparation Products
LEUKOTRIENE D4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7433 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 18521735133 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |