ChemicalBook >> CAS DataBase List >>GLP-1 (7-37)
GLP-1 (7-37)
- CAS No.
- 106612-94-6
- Chemical Name:
- GLP-1 (7-37)
- Synonyms
- Tglp-1;GLP-1, 7-37;HuMan GLP-1;Glp-I (7-37);insulinotropin;GLP-1(7-37), >98%;Human GLP-1 (7-37);GLP-1 acetate salt;GLP-1 (7-37) (HUMAN);GLP-1(7-37) impurity
- CBNumber:
- CB1445727
- Molecular Formula:
- C151H228N40O47
- Molecular Weight:
- 3355.67
- MDL Number:
- MFCD00167940
- MOL File:
- 106612-94-6.mol
Last updated:2024-04-12 23:00:59
| Density | 1.48±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | −20°C |
| solubility | Water:30.0(Max Conc. mg/mL);8.34(Max Conc. mM) |
| form | Lyophilized powder |
| Water Solubility | Soluble in water at 2mg/ml |
| Sequence | H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH |
| CAS DataBase Reference | 106612-94-6 |
| FDA UNII | PI470C66NT |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
GLP-1 (7-37) price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G9416 | Glucagon-Like Peptide 1 Fragment 7-37 human ≥96% (HPLC) | 106612-94-6 | 0.5mg | $530 | 2024-03-01 | Buy |
| Alfa Aesar | J66232 | Glucagon Like Peptide-1 (7-37) | 106612-94-6 | 0.5mg | $191 | 2023-06-20 | Buy |
| Alfa Aesar | J66232 | Glucagon Like Peptide-1 (7-37) | 106612-94-6 | 1mg | $364 | 2023-06-20 | Buy |
| Tocris | 5374 | GLP-1(7-37) | 106612-94-6 | 1 | $458 | 2021-12-16 | Buy |
| ChemScene | CS-5975 | GLP-1(7-37) 99.87% | 106612-94-6 | 5mg | $432 | 2021-12-16 | Buy |
GLP-1 (7-37) Chemical Properties,Uses,Production
Description
GLP-1 (7-37) is an endogenous truncated form of GLP-1 that arises from proglucagon processing in intestinal endocrine L cells, GLP-1 (7-37) acts as a GLP-1 receptor agonist and is an insulinotropic hormone that augments glucose induced insulin secretion. GLP-1 (7-37) and derivatives GLP-1 (9-37) and GLP-1 (28-37) can reduce plaque inflammation and increase phenotypic characteristics of plaque stability in a murine model of atherosclerosis.
Uses
Glucagon-Like Peptide 1 Fragment 7-37 human has been used:
- as a positive control for insulin secretion of pancreatic islets
- to test its effect on insulin response in horse islets
- in combination with mesenchymal stem cells (MSCs) test its protective effects in myocardial infarction
General Description
Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) is an amino-truncated form of GLP-1.
Biochem/physiol Actions
Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) interacts with the GLP-1 receptor (GLP-1r). It mediates insulin release by stimulating the cyclic AMP accumulation in islet cells GLP-l(7-37) is a potential therapeutic agent due to its insulin-secretagogue functionality.
in vitro
In vitro, truncated glucagon-like peptides [GLP-1(7-36)-amide and GLP-1(7-37)] increase insulin secretion in a glucose-dependent manner, and desensitization to the action of GLP-1(7-37) has been demonstrated acutely with high concentrations.
in vivo
GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats. Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM.
storage
Store at -20°C
GLP-1 (7-37) Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 183)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 999 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 881 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Shanghai Getian Industrial Co., LTD | +86-15373193816 +86-15373193816 | mike@ge-tian.com | China | 274 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | +86-411-39042497 +8613921981412 | sales@alphabiopharm.com | China | 886 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from GLP-1 (7-37) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-15 | GLP-1 (7-37)
106612-94-6
|
US $28.00 / box | 1box | 99% | 20000 | Shanghai Getian Industrial Co., LTD | |
 |
2024-05-10 | GLP-1 (7-37)
106612-94-6
|
US $80.00-800.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2024-03-08 | GLP-1 (7-37)
106612-94-6
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd |
-
- GLP-1 (7-37)
106612-94-6
- US $28.00 / box
- 99%
- Shanghai Getian Industrial Co., LTD
-
- GLP-1 (7-37)
106612-94-6
- US $80.00-800.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- GLP-1 (7-37)
106612-94-6
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd
106612-94-6(GLP-1 (7-37))Related Search:
Insulinotropin (human)
Peptide GLP-1 (human glucose-lowering peptide-1)
Glp-I (7-37)
Glucagon like peptide I (7-37)
Glucagon-related peptide (oncorhynchus kisutch), 3-L-glutamic acid-6-L-phenylalanine-9-L-aspartic acid-12-L-serine-15-L-glutamic acid-16-glycine-21-L-isoleucine-24-L-alanine-27-L-valine-28-L-lysine-31-glycine-
Tglp-1
GLP-1, 7-37
Preproglucagon 78-108
GLP-1 (7-37) (huMan, bovine, guinea pig, Mouse, rat)
Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucag
7-37-Glucagon-like peptide I (human)
Human GLP-1 (7-37)
insulinotropin
GLP-1, 7-37, Preproglucagon 78-108
Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
HuMan GLP-1
7-37-Glucagon-likepeptide
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH acetate salt
GLP-1 (7-37) Acetate | Glucagon-Like Peptide 1
l-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alany
PROGLUCAGON (78-108) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
PREPROGLUCAGON 78-108 HUMAN
PREPROGLUCAGON (98-128) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
INSULINOTROPIN (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
GLP-1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)
GLP-1 (7-37) (HUMAN)
GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
GLUCAGON-LIKE PEPTIDE 1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)
GLUCAGON LIKE PEPTIDE-I (7-37), HUMAN
GLUCAGON-LIKE PEPTIDE 1, FRAGMENT 7-37 HUMAN
GLUCAGON-LIKE PEPTIDE 1 (7-37)
GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN)
GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
GLP-1(7-38), Insulinotropin
Glucagon-Like Peptide (GLP) I (7-37)
GLP-1(7-37), >98%
GLP-1(7-37),HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG, >98%
GLP-1(7-37) impurity
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH USP/EP/BP
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GL...
TIANFUCHEM--106612-94-6---H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-
LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-LE-ALA-TRP-LEU-VAL-
LYS-GLY-ARG-GLY-OH
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
Insulinotropin acetate [GLP-1 (7-37)
GLP-1 acetate salt
Glucagon-Like Peptide-1 (7-37)|GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat)
106612-94-6
C151H228N40O47
peptides pharm
peptide