Dibenzepin
- CAS No.
- 4498-32-2
- Chemical Name:
- Dibenzepin
- Synonyms
- HF 1927;Dibenzepin;4498-32-12;5-(2-dimethylaminoethyl)-11-methylbenzo[b][1,4]benzodiazepin-6-one;5-(2-dimethylaminoethyl)-11-methyl-benzo[b][1,4]benzodiazepin-6-one;5-Methyl-10-dimethylaminoethyl-10,11-dihydro-11-oxodibenzo[b,e][1,4]diazepine;5-Methyl-10-[2-(dimethylamino)ethyl]-5H-dibenzo[b,e][1,4]diazepine-11(10H)-one;10-[2-(Dimethylamino)ethyl]-5,10-dihydro-5-methyl-11H-dibenzo[b,e][1,4]diazepin-11-one;10,11-Dihydro-5-methyl-10-[2-(dimethylamino)ethyl]-5H-dibenzo[b,e][1,4]diazepin-11-one;10,11-Dihydro-10-[2-(dimethylamino)ethyl]-5-methyl-5H-dibenzo[b,e][1,4]diazepin-11-one
- CBNumber:
- CB21105957
- Molecular Formula:
- C18H21N3O
- Molecular Weight:
- 295.38
- MDL Number:
- MFCD00865354
- MOL File:
- 4498-32-2.mol
| Melting point | 116-117°C |
|---|---|
| Boiling point | bp0.01 185° |
| Density | 1.1190 (rough estimate) |
| refractive index | 1.5855 (estimate) |
| storage temp. | Refrigerator |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) |
| pka | 8.25(at 25℃) |
| form | Solid |
| color | Light Beige to Brown |
| CAS DataBase Reference | 4498-32-2 |
| FDA UNII | 510SJZ1Y6L |
| ATC code | N06AA08 |
Dibenzepin price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D416920 | Dibenzepin | 4498-32-2 | 50mg | $1355 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21524 | Dibenzepin | 4498-32-2 | 50mg | $1529 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007971 | DIBENZEPIN 95.00% | 4498-32-2 | 50MG | $1871.1 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21524 | Dibenzepin | 4498-32-2 | 2mg | $139.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21524 | Dibenzepin | 4498-32-2 | 5mg | $254.4 | 2021-12-16 | Buy |
Dibenzepin Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Originator
Noveril ,Wander,Switz.,1965
Uses
Antidepressant
Definition
ChEBI: 5-[2-(dimethylamino)ethyl]-11-methyl-6-benzo[b][1,4]benzodiazepinone is a dibenzodiazepine.
Manufacturing Process
4.48 grams of 5-methyl-11-hydroxy-5H-dibenzo[b,e][1,4]diazepine and 0.86
gram of sodium amide were boiled for one hour in 50 ml of absolute dioxane.
After adding a concentrated benzenic solution of β-dimethylamino-ethyl
chloride freshly prepared from 3.75 grams of the hydrochloride with
concentrated sodium hydroxide solution, taking up in benzene and drying the
solution with potash, the mixture was boiled for 16 hours under reflux,
whereupon the reaction mixture was concentrated to dryness and the residue
distributed between ether and water. By exhaustive extraction of the basic
fractions with dilute acetic acid, precipitation with ammonia, taking up the
base in ether and working up the ethereal solution, there was obtained 5.05
grams (85% of the theoretical) of 5-methyl-10-β-dimethylamino-ethyl-10,11-
dihydro-11-oxo-5H-dibenzo[b,e][1,4]diazepine in the form of a viscous
yellowish resin with the boiling point 185°C/0.01mm Hg. The base was
crystallized from acetone-petroleum ether, MP 116°-117°C. Melting point of
the monohydrochloride (from ethanol-ether) 234°-240°C.
Therapeutic Function
Psychostimulant
Dibenzepin Preparation Products And Raw materials
Dibenzepin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9020 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55954 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Shaanxi Xihua Chemical Industry Co., Ltd | 029-81122149 13992773979 | 1088@dideu.com | China | 3667 | 58 |
| Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6018 | 58 |