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D-(-)-MANDELIC ACID BENZYL ESTER

CAS No.
97415-09-3
Chemical Name:
D-(-)-MANDELIC ACID BENZYL ESTER
Synonyms
DOMIT-002;(R)-BENZYL MANDELATE;BENZYL D-(-)-MANDELATE;BENZYL (R)-(-)-MANDELATE;BenzylD-(-)-Mandelate>Benzyl (R)-(-)-mandelate 99%;D-(-)-MANDELIC ACID BENZYL ESTER;-Benzyl 2-hydroxy-2-phenylacetate;(R)-Benzyl 2-hydroxy-2-phenylacetate;Benzyl D-(-)-Mandelate
CBNumber:
CB2116376
Molecular Formula:
C15H14O3
Molecular Weight:
242.27
MDL Number:
MFCD00674031
MOL File:
97415-09-3.mol
MSDS File:
SDS
Last updated:2023-06-08 09:01:56

D-(-)-MANDELIC ACID BENZYL ESTER Properties

Melting point 104-107 °C(lit.)
Boiling point 387℃
Density 1.204
refractive index -34 ° (C=1, CH3CN)
Flash point 163℃
storage temp. Sealed in dry,Room Temperature
solubility DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: 25 mg/ml; Ethanol: 20 mg/ml
pka 12.15±0.20(Predicted)
form powder to crystal
color White to Almost white
optical activity [α]25/D 55°, c = 1 in chloroform
CAS DataBase Reference 97415-09-3

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Safety Statements  24/25
WGK Germany  3
HS Code  29181990
NFPA 704
0
3 0

D-(-)-MANDELIC ACID BENZYL ESTER price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R549800 HYDROXY-PHENYL-ACETIC ACID BENZYL ESTER AldrichCPR 97415-09-3 50MG $29.8 2024-03-01 Buy
Sigma-Aldrich 456497 Benzyl (R)-(?)-mandelate 99% 97415-09-3 5g $69.3 2023-06-20 Buy
TCI Chemical M1354 Benzyl D-(-)-Mandelate >98.0%(GC) 97415-09-3 5g $34 2024-03-01 Buy
TCI Chemical M1354 Benzyl D-(-)-Mandelate >98.0%(GC) 97415-09-3 25g $101 2024-03-01 Buy
Cayman Chemical 10007145 (R)-benzyl Mandelate ≥99% 97415-09-3 1g $11 2024-03-01 Buy
Product number Packaging Price Buy
R549800 50MG $29.8 Buy
456497 5g $69.3 Buy
M1354 5g $34 Buy
M1354 25g $101 Buy
10007145 1g $11 Buy

D-(-)-MANDELIC ACID BENZYL ESTER Chemical Properties,Uses,Production

Description

(R)-benzyl Mandelate is a synthetic intermediate useful for pharmaceutical synthesis.

Uses

D-(-)-Mandelic Acid Benzyl Ester is a useful reagent for the preparation of a pharmaceutical composition for treating atopic dermatitis.

Uses

Benzyl (R)-(-)-mandelate can be employed as reactant to synthesize:

  • (S)-α-Hydroxy-N-(2-phenylethyl)benzenepropanamide (α-hydroxyamides) by enzyme catalyzed amidation reaction.
  • Optically pure (R)- monomethyl esters of 3-[(tert-butyldimethylsilyl)oxy]pentanedioic acid, which is employed in the preparation of HMG-CoA reductase inhibitors.
  • O-Ibuprofenylmandelic acid via acylation reaction with optically active ibuprofen and subsequent hydrogenation.
  • Benzyl (R)-2-fluoro-2-phenylacetate via deoxyfluorination of alcohols using AlkylFluor.
It can also be used to prepare HMG-CoA reductase inhibitors.

D-(-)-MANDELIC ACID BENZYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 142)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15954 58
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2966 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 2577 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10297 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9126 58

View Lastest Price from D-(-)-MANDELIC ACID BENZYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D-(-)-MANDELIC ACID BENZYL ESTER pictures 2022-09-28 D-(-)-MANDELIC ACID BENZYL ESTER
97415-09-3
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
D-(-)-Mandelic acid benzyl ester  pictures 2020-01-05 D-(-)-Mandelic acid benzyl ester
97415-09-3
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
D-(-)-MANDELIC ACID BENZYL ESTER      pictures 2019-07-06 D-(-)-MANDELIC ACID BENZYL ESTER
97415-09-3
US $20.00 / KG 10KG 98% 100kg Career Henan Chemical Co

D-(-)-MANDELIC ACID BENZYL ESTER Spectrum

(R)-BENZYL MANDELATE D-(-)-MANDELIC ACID BENZYL ESTER BENZYL D-(-)-MANDELATE BENZYL (R)-(-)-MANDELATE ALPHA-HYDROXY-BENZENEACETIC ACID, PHENYLMETHYL ESTER Benzyl-(R)-Mandelate / Benzyl-(D)-Mandelate (R)-Benzyl 2-hydroxy-2-phenylacetate Benzeneacetic acid, α-hydroxy-, phenylmethyl ester, (αR)- Benzyl (R)-(-)-mandelate 99% Benzyl D-(-)-Mandelate -Benzyl 2-hydroxy-2-phenylacetate benzyl (2R)-2-hydroxy-2-phenylacetate DOMIT-002 BenzylD-(-)-Mandelate> D-(-)-MANDELIC ACID BENZYL ESTER ISO 9001:2015 REACH 97415-09-3 Asymmetric Synthesis Chiral Building Blocks Esters (Chiral) Esters Organic Building Blocks Chiral Building Blocks Esters (Chiral) Synthetic Organic Chemistry Chiral Building Blocks Esters Organic Building Blocks