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ChemicalBook >> CAS DataBase List >>(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Structure
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole structure
CAS No.
112022-81-8
Chemical Name:
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
Synonyms
(S)-2-METHYL-CBS-OXAZABOROLIDINE;(S)-1-METHYL-3,3-DIPHENYLHEXAHYDROPYRROLO[1,2-C][1,3,2]OXAZABOROLE;(S)-ME CBS;(S)-Me-CBS Catalyst;(S)-2-METHYL-CBS-OXAZABOROL;(S)-(-)-2-METHYL-CBS-OXAZABOROLIDINE;(s)-(-)-2-methyl-cbs-oxazaborolidine solution;(S)-5,5-DIPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABOROLIDINE;(S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(S)-Methyloxazaborolidine;(s)-methyl
CBNumber:
CB3106062
Molecular Formula:
C18H20BNO
Molecular Weight:
277.17
MDL Number:
MFCD00078439
MOL File:
112022-81-8.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
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(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Properties

Melting point 115-117°C
Boiling point 111 °C
Density 0.93 g/mL at 20 °C(lit.)
refractive index -68 ° (C=1, MeOH)
Flash point 40 °F
storage temp. room temp
pka 1.02±0.40(Predicted)
form Liquid
color Colorless to amber
Water Solubility Hydrolyzes in water.
Sensitive Air & Moisture Sensitive
BRN 8492123
Exposure limits ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3)
InChIKey VMKAFJQFKBASMU-KRWDZBQOSA-N
CAS DataBase Reference 112022-81-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318
Precautionary statements  P280-P301+P312+P330-P305+P351+P338+P310
Hazard Codes  Xi,Xn,F
Risk Statements  36/37/38-67-65-63-48/20-11-19-40
Safety Statements  26-62-36/37-33-29-16
RIDADR  UN 1294 3/PG 2
WGK Germany  3
F  10-21
HazardClass  3
PackingGroup  II
HS Code  29349990
NFPA 704
3
3 1

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 457701 (S)-(?)-2-Methyl-CBS-oxazaborolidine solution 1 M in toluene 112022-81-8 5ml $98.6 2024-03-01 Buy
Sigma-Aldrich 457701 (S)-(?)-2-Methyl-CBS-oxazaborolidine solution 1 M in toluene 112022-81-8 25ml $345 2024-03-01 Buy
TCI Chemical D2131 (S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine >98.0%(T) 112022-81-8 1g $84 2024-03-01 Buy
TCI Chemical D2131 (S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine >98.0%(T) 112022-81-8 5g $331 2024-03-01 Buy
Alfa Aesar L09219 (S)-2-Methyl-CBS-oxazaborolidine monohydrate, 94% 112022-81-8 1g $272 2021-12-16 Buy
Product number Packaging Price Buy
457701 5ml $98.6 Buy
457701 25ml $345 Buy
D2131 1g $84 Buy
D2131 5g $331 Buy
L09219 1g $272 Buy

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Chemical Properties,Uses,Production

Reaction

  1. Convenient catalyst for the enantioselective borane reduction of ketones at ambient temperatures.
  2. Asymmetric synthesis of α-chiral hydroxyalkylphosphines via a catalytic, enantioselective reduction of acylphosphines.
  3. Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: Stereospecific formation of diarylalkanes and triarylmethanes.
  4. Enantioselective reduction of prochiral ketones with NaBH4/Me2SO4/(S)-Me-CBS.
Reactions of 112022-81-8

Chemical Properties

Colorless to yellow liquid

Uses

(S)-2-Methyl-CBS-oxazaborolidine is used as an oxazaborolidine catalyst. It is also employed in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols and propargyl alcohols. It is an anhydrous catalyst for 'CBS' reduction reaction.

Uses

suzuki reaction

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole synthesis

13061-96-6
22348-32-9
112022-81-8
Synthesis of (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole from Methylboronic acid and (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Preparation Products And Raw materials

Raw materials

Trimethylboroxine PHENYLMAGNESIUM BROMIDE L-Proline Tetrahydrofuran Dichloromethane
Thionyl chloride

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Preparation Products

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Suppliers

Global( 272)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15957 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21689 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Zjartschem 		+86-571-8723 8903 jocelynpan@zjarts.com jocelynpan@zjarts.com CHINA 993 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 7019 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Shanghai Yingrui Biopharma Co., Ltd. 		60
Nanjing Finetech Chemical Co., Ltd. 		55
Zjartschem 		58
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58

View Lastest Price from (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole pictures 2022-09-27 (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
112022-81-8
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
(S)-()-2-Methyl-CBS-oxazaborolidine solution pictures 2021-07-02 (S)-()-2-Methyl-CBS-oxazaborolidine solution
112022-81-8
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole pictures 2019-07-06 (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
112022-81-8
 US $1.00 / kg 1kg 95%-99% as request Career Henan Chemical Co

112022-81-8((S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole)Related Search:

(4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone Phosphorus trichloride 4-Methoxybenzoic acid Lithium hydride Tetrahydrofuran
CATECHOLBORANE (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol L-(+)-Prolinol Methylboronic acid (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
(R)-Tetrahydro-1,3,3-triphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxaborole, 99% (R)-Phenyl oxazaborolidine (S)-O-TOLYL-CBS-OXAZABOROLIDINE, 0.5M I& (S)-Tetrahydro-1,3,3-triphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxaborole, 99% (S)-Phenyl oxazaborolidine (S)-CBS-BORANE COMPLEX (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
(R)-O-TOLYL-CBS-OXAZABOROLIDINE, 0.5M I&

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(S)-1-METHYL-3,3-DIPHENYL-TETRAHYDRO-PYRROLO[1,2C][1,3,2]OXAZABOROLE α,α-diphenyl-l-prolinol methylboronic acid cycl-amide-ester (S)-(+)-Methyl-CBS-oxazaborolidine (S)-5,5-DIPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABOROLIDINE 98+% (S)-METHYL-CBS-OXAZABOROLIDINE,1M SOLN.IN TOLUENE (S)-Methyl oxazaborolidine, in toluene, 1M solution (S)-3,3-DIPHENYL-1-METHYLTETRAHYDRO-3H-P YRROLO-OXAZABOROLE (S)-2-METHYL-CBS-OXAZABOROLIDINE, 1M SOL UTION IN TOLUENE (S)-2-METHYL-CBS-OXAZABOROLIDINE, 1M IN& (S)-Methyloxazaborolidine,1-1.5Mintoluene[(S)-MeCBS]CoreyCatalyst (s)-2-methyl-cbs-oxazaborolidine, 1m soln. in toluene (S)-1-Methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2c][1,3,2]oxazaborole, (S)-3,3-Diphenyl-1-methyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole, (S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, α,α-Diphenyl-L-prolinol methylboronic acid cycl-amide ester (S)-Tetrahydro-1-methyl-3,3-triphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 1-1.5M in toluene [(S)-Methyl oxazaborolidine] Corey Catalyst (3aS)-1-Methyl-3,3-diphenyl-3aβ,4,5,6-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole (3aS)-1-Methyl-3,3-diphenyl-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole (3aS)-3,3aβ,4,5-Tetrahydro-1-methyl-3,3-diphenyl-6H-1-bora-2-oxa-6a-azapentalene (3aS)-3,3-Diphenyl-1-methyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole (3aS)-3aβ,4,5,6-Tetrahydro-1-methyl-3,3-diphenyl-3H-pyrrolo[1,2-c][1,3,2]oxazaborole (S)-()-2-Methyl-CBS-oxazaborolidine solution 1 M in THF (S)-2-Methyl-CBS-oxazaborolidine (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole (S)-(-)-2-Methyl-CBS-oxazaborolidine >=95.0% (S)-(-)-2-Methyl-CBS-oxazaborolindine (S)-2-methyl-CBS-oxazaborolidine(1mol/L) (S)-2-methyl-CBS-oxazaborolidine(solid) (3aβ)-1-Methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole 1-(S)-methyl CBS oxazaborolidine (S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole,0.9-1.1Mintoluene[(S)-Methyloxazaborolidine]CoreyCatalyst (S)-(-)-2-METHYL-CBS-[1,3,2]OXAZABOROLIDINE IN,TOLUENE (S)-2-Methyl-CBS-oxazaborolidine ,98% ALPHA,ALPHA-DIPHENYL-L-PROLINOL METHYLBORONIC ACID CYCL-AMIDE ESTER (S)-(-)-2-Methyl-CBS-oxazaborolidine, 1M solution in toluene, AcroSeal 1-Methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole (S)-2-METHYL-CBS-OXAZABOROLIDINE MONOHYDRATE (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole (S)-3,3-DIPHENYL-1-METHYLTETRAHYDRO-1H,3H-PYRROLO[1,2-C][1,3,2]OXAZABOROLE (S)-3,3-DIPHENYL-1-METHYLTETRAHYDRO-3H-PYRROLO-[1,2-C][1,3,2]OXAZABOROLE (S)-METHYL OXAZABOROLIDINE (S)-TETRAHYDRO-1-METHYL-3,3-DIPHENYL-1H,3H PYRROLO[1,2-C][1,3,2] OXAZABOROLE (s)-methyl (s)-methyloxazaborolidine,(s)-mecbs,in (s)-methyloxazaborolidine,(s)-mecbs,intoluene (S)-Methyloxazaborolidine,1-1.5Mintoluene[(S)-MeCBS] (S)-Tetrahydro-1-Methyl-3 0.9-1.1Mintoluene[(S)-Methyloxazaborolidine]CoreyCatalyst (S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrole[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(S)-Methyloxazaborolidine] Corey Catalyst (S)-3,3-Diphenyl-1-methyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole (S)-Me-CBS Catalyst (S)-Methyl oxazaborolidine in toluene 1M (S)-Tetrahydro-1-Methyl-3,3-Triphenyl-1H,3H-Pyrrolo[1,2-c][1,3,2]Oxazaborole (S)-Methyloxazaborolidine 1M in toluene 1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole,tetrahydro-1-Methyl-3,3-diphenyl-, (3aS)- (S)-(-)-2-Methyl-CBS-oxazaborolidine, 1.0 M solution in toluene (S)-(-)-2-Methyl-CBS-oxazaborolidine, 1.0 M solution in THF (S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(S)-Methyloxazaborolidine] (S)-CBS Catalyst (3aS)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole (S)-(-)-2-Methyl-CBS-oxazaborolidine, 1.0 M solution in toluene, J&KSeal (S)-(-)-2-MethyL (S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine - 1.0M in toluene (S) - 2-methyl-cbs-oxazolidine