Tifenamil
- CAS No.
- 82-99-5
- Chemical Name:
- Tifenamil
- Synonyms
- thiphenamil;Diphenylthioacetic acid S-[2-(diethylamino)ethyl];Diphenylthioacetic acid S-[2-(diethylamino)ethyl] ester;Benzeneethanethioic acid, α-phenyl-, S-[2-(diethylamino)ethyl] ester
- CBNumber:
- CB31179913
- Molecular Formula:
- C20H25NOS
- Molecular Weight:
- 327.49
- MDL Number:
- MFCD00396147
- MOL File:
- 82-99-5.mol
| Melting point | 35-36 °C |
|---|---|
| Boiling point | 199-200 °C |
| Density | 1.079±0.06 g/cm3(Predicted) |
| pka | 9.42±0.25(Predicted) |
| FDA UNII | GX4D5197DT |
Tifenamil Chemical Properties,Uses,Production
Originator
Trocinate,Poythress,US,1950
Definition
ChEBI: Tifenamil is a diarylmethane.
Manufacturing Process
The following procedure is described in US Patent 2,510,773: To an ice-cold solution of 13.3 grams of 2-diethylaminoethanethiol in 100 cc of dry benzene is slowly added a solution of 23.05 grams of diphenylacetyl chloride in 200 cc of dry benzene. The mixture is stirred 2 hours, then heated to dissolve the fine white solid that is formed. Upon cooling 31.3 grams of 2- diethylaminoethyl diphenylthiolacetate hydrochloride precipitates. It recrystallizes from a mixture of benzene and petroleum ether (BP 60° to 70°C) as rosettes of tiny needles and melts at 129° to 130°C. From a mixture of absolute ethanol and ethyl acetate it recrystallizes as large, almost transparent prisms.
brand name
Tifenamil is INN.
Therapeutic Function
Spasmolytic
Tifenamil Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Princeton BioMolecular Research, Inc. | -- | info@princetonbio.com | United States | 6935 | 51 |
| Supplier | Advantage |
|---|---|
| Princeton BioMolecular Research, Inc. | 51 |