ChemicalBook >> CAS DataBase List >>BIOTIN HYDRAZIDE
BIOTIN HYDRAZIDE
- CAS No.
- 66640-86-6
- Chemical Name:
- BIOTIN HYDRAZIDE
- Synonyms
- Biotin-Hz;Biotin-NHNH2;CAS_66640-86-6;5-((3aS,4S,6aR);BIOTIN-Hydrazid;BIOTIN-HYDRAZIDE;BIOTIN HYDRAZIDE;Biontin-Hydrazide;Biotin Impurity 32;Biotinyl hydrazine
- CBNumber:
- CB3175354
- Molecular Formula:
- C10H18N4O2S
- Molecular Weight:
- 258.34
- MDL Number:
- MFCD00078532
- MOL File:
- 66640-86-6.mol
- MSDS File:
- SDS
Last updated:2023-09-20 16:43:00
| Melting point | 245-247 °C |
|---|---|
| Boiling point | 633.1±40.0 °C(Predicted) |
| Density | 1.243±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≤20 mg/mL |
| pka | 13.25±0.35(Predicted) |
| form | powder |
| color | White to Almost white |
| BRN | 28347 |
| InChIKey | KOZWHQPRAOJMBN-ZKWXMUAHSA-N |
| CAS DataBase Reference | 66640-86-6(CAS DataBase Reference) |
| FDA UNII | BD4VQ48JNV |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
BIOTIN HYDRAZIDE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B7639 | (+)-Biotin hydrazide ≥97% (TLC), powder | 66640-86-6 | 100mg | $102 | 2024-03-01 | Buy |
| Sigma-Aldrich | B7639 | (+)-Biotin hydrazide ≥97% (TLC), powder | 66640-86-6 | 1g | $520 | 2024-03-01 | Buy |
| TCI Chemical | B2431 | Biotin Hydrazide >98.0%(HPLC) | 66640-86-6 | 25mg | $32 | 2024-03-01 | Buy |
| TCI Chemical | B2431 | Biotin Hydrazide >98.0%(HPLC) | 66640-86-6 | 100mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 18418 | Biotin hydrazide ≥95% | 66640-86-6 | 100mg | $57 | 2024-03-01 | Buy |
BIOTIN HYDRAZIDE Chemical Properties,Uses,Production
Description
Biotin hydrazide is a biotinyl derivative used to label surface functional groups, antibodies, lectins, sugars, nucleic acids, or molecules with free carboxylic or keto groups. Biotin hydrazide is used as a probe for determining protein carbonylation, an irreversible posttranslational modification resulting from the actions of reactive oxygen species or lipid oxidation products. The reaction of this probe is direct and does not require catalysts or reducing agents.
Chemical Properties
3.6
Uses
Biotin Hydrazide is a carbohydrate reactive biotinylation reagent used predominately for labeling monoclonal antibodies, unpaired cytosine residues in nucleic acids and glycoproteins.
Uses
aldehyde reactive biotinylation reagent
Uses
(+)-Biotin hydrazide has been used:
- the modification of alginate
- for the labelling of mitochondrial proteins from non-muscle tissues
- as a component of glycoprotein staining solution
- in periodic acid-biotin-hydrazide (PABH) assay for mucins
- for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups.
- for coupling to glycoproteins through the carbohydrate by hydrazone formation
General Description
Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties. Biotin hydrazide can be used to prepare biotin-conjugated alginate. It can also be used for covalent attachment to PAAc via carbodi-imide cross linking.
Purification Methods
Wash the hydrazide with H2O, dry it, wash it with MeOH then Et2O, and dry. Recrystallise it from hot H2O (clusters of prisms) [Hofmann et al. J Biol Chem 144 513 1942]. [Beilstein 27 III/IV 7980.]
BIOTIN HYDRAZIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 215)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2169 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
View Lastest Price from BIOTIN HYDRAZIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | Biotin hydrazide HCl
66640-86-6
|
US $0.00 / g | 5g | >95.00% | 5g | Xian confluore Biological Technology Co., Ltd. | |
 |
2021-07-13 | BIOTIN HYDRAZIDE
66640-86-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | BIOTIN HYDRAZIDE
66640-86-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Biotin hydrazide HCl
66640-86-6
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
-
- BIOTIN HYDRAZIDE
66640-86-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- BIOTIN HYDRAZIDE
66640-86-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
BIOTIN (LONG ARM) HYDRAZIDE
(+)-BIOTIN HYDRAZIDE
BIOTIN HYDRAZIDE
1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazid e, (3aS,4S,6aR)-
BIOTIN-HYDRAZIDE
Biotin-NHNH2
D-Biotin Hydrazide
1H-Thieno(3,4-D)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3as-(3aalpha,4beta,6aalpha))-
Biotin-Hz
5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanehydrazide
Biontin-Hydrazide
-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)
5-((3aS,4S,6aR)
CAS_66640-86-6
Biotin Hydrazide >
Biotin Impurity 32
Biotinyl hydrazine
(+)-Biotin-hydrazide
5-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanehydrazide
Biotin hydrazide *CAS 66640-86-6*
Biotin hydrazide (5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanehydrazide)
Biotin hydrazide HCl
BIOTIN-Hydrazid
1H-Pyrazole,3,5-bis(4-chlorophenyl)-4,8-dihydro-
5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide
66640-86-6
666640-86-6
C10H18N4O2S
C10H18N4SO2
Antibody Modification
Antibody Labeling
Antibodies
BioChemical
Labeling with Biotin
Supplementary Products
Biotinylation Reagents
biotinyl
BiotinylationReagents
Biotin Labeling ReagentsGlycobiology
Detection of Biotin Labeled Glycoproteins on Western BlotsAntibody Modification
Labeling with Biotin
Antibody Labeling
Biotin/Avidin
Glycoprotein Detection
Supplementary Products