ChemicalBook >> CAS DataBase List >>BIOTIN-NHS

BIOTIN-NHS

CAS No.
35013-72-0
Chemical Name:
BIOTIN-NHS
Synonyms
NHS-BIOTIN;BIOTIN-OSU;BNHS;2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanoate;(2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate;BHSE;BIOTIN SE;BIOTIN-NHS;D-BIOTIN, SE;NHS-D-BIOTIN
CBNumber:
CB7371998
Molecular Formula:
C14H19N3O5S
Molecular Weight:
341.38
MDL Number:
MFCD00078531
MOL File:
35013-72-0.mol
MSDS File:
SDS
Last updated:2023-06-08 09:01:53

BIOTIN-NHS Properties

Melting point 212-214 °C
Density 1.45±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: ≤50 mg/mL Stable for at least one month in dry DMF
form powder
pka 13.89±0.40(Predicted)
color White to off-white
BRN 4720781
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 35013-72-0(CAS DataBase Reference)
FDA UNII 30M534A3CQ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  EUH210
Precautionary statements  P271-P261-P280
Safety Statements  22-24/25
WGK Germany  3
10-23
HS Code  2934 99 90
NFPA 704
1
0 0

BIOTIN-NHS price More Price(79)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H1759 (+)-Biotin N-hydroxysuccinimide ester ≥98% (HPLC), powder 35013-72-0 5mg $26.7 2024-03-01 Buy
Sigma-Aldrich H1759 (+)-Biotin N-hydroxysuccinimide ester ≥98% (HPLC), powder 35013-72-0 1g $947 2024-03-01 Buy
Sigma-Aldrich 8.51023 Biotin-OSu Novabiochem? 35013-72-0 1g $254 2024-03-01 Buy
Sigma-Aldrich 203112 Biotin-NHS 35013-72-0 250MG $401 2024-03-01 Buy
TCI Chemical S0491 N-Succinimidyl D-Biotinate >97.0%(HPLC)(N) 35013-72-0 100mg $119 2024-03-01 Buy
Product number Packaging Price Buy
H1759 5mg $26.7 Buy
H1759 1g $947 Buy
8.51023 1g $254 Buy
203112 250MG $401 Buy
S0491 100mg $119 Buy

BIOTIN-NHS Chemical Properties,Uses,Production

Description

N-Hydroxysuccinimide (NHS) activates carboxylic acid groups (on biotin) to facilitate coupling reactions. Biotin-NHS is a compound used to attach biotin to primary amines under alkaline conditions (pH~8-9). For example, lysines on the surface of proteins, including antibodies, are ideal targets for biotinylation with this compound.

Chemical Properties

White Solid

Uses

Biotin-NHS is used in the biotinylation of proteins and peptides. Couples with primary amine in the pH range 6.5-8.5.

Uses

amine reactive biotinylation reagent

Uses

Amino reactive biotin reagent for preparing biotinylated surfaces or polypeptides.

Purification Methods

Recrystallise the ester from refluxing isoPrOH and dry it in a vacuum over P2O5 + KOH. [Jasiewicz et al. Exp Cell Biol 100 213 1976.]

74124-79-1
58-85-5
35013-72-0
Synthesis of BIOTIN-NHS from N,N'-Disuccinimidyl carbonate and D-Biotin
Global( 374)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15957 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21689 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58

View Lastest Price from BIOTIN-NHS manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-NHS ester pictures 2024-04-02 Biotin-NHS ester
35013-72-0
US $0.00 / g 25g >95.00% 25g Xian confluore Biological Technology Co., Ltd.
BIOTIN-NHS pictures 2021-07-13 BIOTIN-NHS
35013-72-0
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
BIOTIN-NHS pictures 2021-07-09 BIOTIN-NHS
35013-72-0
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • Biotin-NHS ester pictures
  • Biotin-NHS ester
    35013-72-0
  • US $0.00 / g
  • >95.00%
  • Xian confluore Biological Technology Co., Ltd.
  • BIOTIN-NHS pictures
  • BIOTIN-NHS
    35013-72-0
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • BIOTIN-NHS pictures
  • BIOTIN-NHS
    35013-72-0
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

BIOTIN-NHS Spectrum

(+)-biotin-n-hydroxysuccimide ester n-hydroxysuccimidobiotin BIOTIN-OSU: N-HYDROXYSUCCINIMIDOBIOTIN d-Biotin NHS ester 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID 2,5-DIOXO-PYRROLIDIN-1-YL ESTER D-(+)BIOTIN N-HYDROXYSUCCINIMIDE ESTER D-BIOTIN-N-HYDROXYSUCCINIMIDE ESTER D-BIOTIN, SE D-BIOTIN, SUCCINIMIDYL ESTER D-BIOTINYL-OSU (+)-BIOTIN N-SUCCINIMIDYL ESTER BIOTIN-N-HYDROXYSUCCINIMIDE (+)-BIOTIN-N-HYDROXYSUCCINIMIDE ESTER BIOTIN-N-HYDROXYSUCCINIMIDE ESTER BIOTIN-NHS BIOTIN (LONG ARM) NHS BIOTIN SE BIOTIN SUCCINIMIDYL ESTER BIOTINYL-N-HYDROXY-SUCCINIMIDE (+)-BIOTINYL-N-SUCCINIMIDYL ESTER SUCCINIMIDO-(+)-BIOTIN SUCCINIMIDYL D-BIOTIN N-HYDROXYSUCCINIMIDOBIOTIN NHS-D-BIOTIN N-SUCCINIMIDYL D-BIOTINATE N-SUCCINIMIDO-(+)-BIOTIN N-Hydroxysuccinimidyl)biotin (+)-Biotin-NHS Ester 2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR) 2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentano Biotin-OSu Novabiochem N-Succinimidyl-D-biotin D-Biotin N-Succinimidyl Ester N-(D-Biotinyloxy)succinimide (+)-Biotin N-succinimidyl ester, d-Biotin NHS ester, Biotinyl-N-hydroxy-succinimide, BNHS, N-Hydroxysuccinimidobiotin, N-Succinimidyl D-biotinate, NHS-Biotin 1-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]-2,5-pyrrolidinedione BHSE (+)-Biotin N-hydroxysuccinimide ester Biotin-NHS N-Hydroxysuccimidobiotin (+)-Biotin N-hydroxysuccinimide ester,(+)-Biotin N-succinimidyl ester, d-Biotin NHS ester, BNHS, Biotinyl-N-hydroxy-succinimide, N-Hydroxysuccinimidobiotin, N-Succinimidyl D-biotinate, NHS-Biotin BIOTIN-NHS (+)-Biotin N-hydroxysucciniMide ester Hexahydro-2-oxo- D-Biotin N-Succinimidyl Ester N-(D-Biotinyloxy)succinimide BNHS, Biotin-NHS BNHS/NHS-Biotin Biotin, succinimidyl ester *CAS 35013-72-0* (+)-Biotin-NHS:BIOTIN-NHS N-Hydroxysuccinimido Biotin、BNHS (+)-Biotin N-hydroxysuccinimide ester(Biotin-NHS) 2,5-Dioxo-1-pyrrolidinyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate Biotin NHS【2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate】 CAS_35013-72-0 Biotin-N-succinimidyl N-SuccinimidylD-Biotinate> N-Succinimidyl D-Biotin (Biotin-OSu) 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, 2,5-dioxo-1-pyrrolidinyl ester, (3aS,4S,6aR)- (+)-Biotin-NHS 2,5-Pyrrolidinedione,1-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]-