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ChemicalBook >> CAS DataBase List >>[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper

[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper

[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper Structure
[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper structure
CAS No.
68341-09-3
Chemical Name:
[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper
Synonyms
CUAM;Cu-ASTM;Cu-ATSM;CuII(atsm);Cu-ASTM >=98% (HPLC);Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II);[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper
CBNumber:
CB32750504
Molecular Formula:
C8H14CuN6S2
Molecular Weight:
321.91296
MDL Number:
MFCD20275141
MOL File:
68341-09-3.mol
Last updated:2023-05-18 11:31:20
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[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper Properties

storage temp. 2-8°C
solubility DMSO: soluble10mg/mL, clear
form powder
color brown to dark red-brown
FDA UNII 0YDK1H9L3A

SAFETY

Risk and Safety Statements

WGK Germany  3

[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0769 Cu-ASTM ≥98% (HPLC) 68341-09-3 5mg $123 2024-03-01 Buy
Sigma-Aldrich SML0769 Cu-ASTM ≥98% (HPLC) 68341-09-3 25mg $482 2024-03-01 Buy
Cayman Chemical 17122 Cu-ATSM ≥95% 68341-09-3 1mg $32 2024-03-01 Buy
Cayman Chemical 17122 Cu-ATSM ≥95% 68341-09-3 5mg $93 2024-03-01 Buy
Cayman Chemical 17122 Cu-ATSM ≥95% 68341-09-3 10mg $169 2024-03-01 Buy
Product number Packaging Price Buy
SML0769 5mg $123 Buy
SML0769 25mg $482 Buy
17122 1mg $32 Buy
17122 5mg $93 Buy
17122 10mg $169 Buy

[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper Chemical Properties,Uses,Production

Uses

Cu-ATSM is preclinically used as a potential therapy for ALS (amyotrophic lateral sclerosis). A potential anti-Alzheimer''s agent.

Biochem/physiol Actions

Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that specifically inhibits the action of peroxynitrite on Cu,Zn superoxide dismutase (SOD1) and subsequent nitration of cellular proteins. CuII(ATSM) significantly delayed onset of disease (paralysis and prolonged lifespan) in amyotrophic lateral sclerosis (ALS) mice model. Also, Cu-ATSM was reported to lower lipid peroxidation in a model of ischemicreperfusion injury. Cu-ATSM subsequently was shown to inhibit ferroptosis with a potency similar to Liproxstatin-1.

[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper Preparation Products And Raw materials

Raw materials

Preparation Products

[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21688 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
YangZhou Ruihong Biotech Co., Ltd. 015380367604 15380367604 China 508 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3501 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Taizhou Nanfeng Pharmaceutical Research Institute 3821987872 nanfengdrug@163.com China 15323 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Aladdin Scientific 		58
YangZhou Ruihong Biotech Co., Ltd. 55
Sigma-Aldrich 80
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Taizhou Nanfeng Pharmaceutical Research Institute 58
MedBioPharmaceutical Technology Inc 58
[[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper Cu-ASTM CuII(atsm) Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) CUAM Cu-ATSM Cu-ASTM >=98% (HPLC) 68341-09-3