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(D-Ala2)-Leu-Enkephalin

CAS No.
64963-01-5
Chemical Name:
(D-Ala2)-Leu-Enkephalin
Synonyms
(D-ALA2)-LEU-ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;D-ALA2-LEU5-ENKEPHALIN;(D-Ala)-Leu-Enkephalin;Tyr-D-Ala-Gly-Phe-Leu-OH;Pentapeptide-3/Leuphasyl;H-TYR-D-ALA-GLY-PHE-LEU-OH;Leuphasyl / Pentapeptide-3;[D-ALA2]-LEUCINE ENKEPHALIN;Leuphasyl / Pentapeptide-18
CBNumber:
CB3667734
Molecular Formula:
C29H39N5O7
Molecular Weight:
569.65
MDL Number:
MFCD00076409
MOL File:
64963-01-5.mol
Last updated:2024-05-11 10:19:09

(D-Ala2)-Leu-Enkephalin Properties

Melting point 160-163.5 °C
Boiling point 991.9±65.0 °C(Predicted)
Density 1.257±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility DMF (Slightly), DMSO (Slightly)
form Solid
pka 3.40±0.10(Predicted)
color White to Off-White
InChIKey ZHUJMSMQIPIPTF-JMBSJVKXSA-N
SMILES C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N
FDA UNII PO4D55T1IG

SAFETY

Risk and Safety Statements

WGK Germany  3

(D-Ala2)-Leu-Enkephalin price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E5008 [D-Ala2]-Leucine enkephalin ≥97% (HPLC) 64963-01-5 5mg $98.9 2024-03-01 Buy
ChemScene CS-5905 [D-Ala2]-Leucine enkephalin 99.77% 64963-01-5 10mg $108 2021-12-16 Buy
Biosynth Carbosynth FA108766 (D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH 64963-01-5 25mg $181 2021-12-16 Buy
ChemScene CS-5905 [D-Ala2]-Leucine enkephalin 99.77% 64963-01-5 50mg $420 2021-12-16 Buy
Activate Scientific AS112962 [D-Ala2]-Leucine enkephalin 97% 64963-01-5 25mg $424 2021-12-16 Buy
Product number Packaging Price Buy
E5008 5mg $98.9 Buy
CS-5905 10mg $108 Buy
FA108766 25mg $181 Buy
CS-5905 50mg $420 Buy
AS112962 25mg $424 Buy

(D-Ala2)-Leu-Enkephalin Chemical Properties,Uses,Production

Definition

The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.

benefits

(D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions.

References

[1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644.

(D-Ala2)-Leu-Enkephalin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 203)Suppliers
Supplier Tel Email Country ProdList Advantage
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
Shanghai Yunao International Trade Co., Ltd
+8617621705551 asdf@shanghaihg.cn China 265 58
Wuhan Cell Pharmaceutical Co., Ltd
+86-13129979210 +86-13129979210 sales@cellwh.com China 376 58
Henan Tengmao Chemical Technology Co. LTD
+8615238638457 salesvip2@hntmhg.com China 415 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Shanghai Affida new material science and technology center
+undefined15081010295 admin@oudaxin.com China 390 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 952 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 1142 58
Shanghai Getian Industrial Co., LTD
+86-15373193816 +86-15373193816 mike@ge-tian.com China 274 58
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58

View Lastest Price from (D-Ala2)-Leu-Enkephalin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Leuphasyl;Pentapeptide-18 pictures 2024-05-31 Leuphasyl;Pentapeptide-18
64963-01-5
US $1.00 / kit 1kit 99% 1000kit Wuhan Cell Pharmaceutical Co., Ltd
Pentapeptide-18 pictures 2024-05-31 Pentapeptide-18
64963-01-5
US $30.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
Leuphasyl;Pentapeptide-18 pictures 2024-05-29 Leuphasyl;Pentapeptide-18
64963-01-5
US $0.00-0.00 / KG 1KG 99 10 tons/per week Shanghai Affida new material science and technology center
  • Pentapeptide-18 pictures
  • Pentapeptide-18
    64963-01-5
  • US $30.00 / kg
  • 99%
  • hebei hongtan Biotechnology Co., Ltd
H-TYR-D-ALA-GLY-PHE-LEU-OH D-ALA2-LEU5-ENKEPHALIN [D-ALA2]-LEUCINE ENKEPHALIN TYR-D-ALA-GLY-PHE-LEU N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-L-leucine (D-alanine2)leucine enkephalin L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH Tyr-D-Ala-Gly-Phe-Leu-OH 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methyl-valeric acid 2-[[2-[2-[2-[[2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid [D-Ala2]-Leucine enkephalin,Tyr-D-Ala-Gly-Phe-Leu Pentapeptide-3/Leuphasyl L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-L-leucine Tyrosyl-D-alanylglycylphenylalanylleucine Leuphasyl / Pentapeptide-3 Lab Supply High Purity Pentapeptide-18 Powder CAS 64963-01-5 with Best Price TYR-D-ALA-GLY-PHE-LEU USP/EP/BP 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoicaci L-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl- Pentapeptide-18/Leuphasyl with reduce facial muscle Leuphasyl / Pentapeptide-18 [D-Ala2]leucine-enkephalin,Tyr-D-Ala-Gly-Phe-Leu, >99% [D-ALA2]LEUCINE-ENKEPHALIN, >99% (D-Ala)-Leu-Enkephalin (D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH (D-ALA2)-LEU-ENKEPHALIN 64963-01-5 C29H39N5O7 Enkephalins Opioid Peptides Peptides Biochemicals and Reagents Amino Acids and Peptides BioChemical