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PD 123319 ditrifluoroacetate

PD 123319 ditrifluoroacetate Structure
PD 123319 ditrifluoroacetate structure
CAS No.
130663-39-7
Chemical Name:
PD 123319 ditrifluoroacetate
Synonyms
CS-953;PD 123,319;PD123319 TFA;PD123319, >=98%;(S)-(+)-PD 123319;ditrifluoroacetate;PD-123319 TFA salt;PD-123319 free base;PD 123319 ditrifluor;PD 123,319 DITRIFLUOROACETATE
CBNumber:
CB3669147
Molecular Formula:
C31H32N4O3
Molecular Weight:
508.61
MDL Number:
MFCD00896427
MOL File:
130663-39-7.mol
MSDS File:
SDS
Last updated:2023-05-18 11:30:59
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PD 123319 ditrifluoroacetate Properties

Boiling point 775.8±60.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: 12 mg/mL
form powder
pka 2.80±0.20(Predicted)
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3

PD 123319 ditrifluoroacetate price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1361 PD123319ditrifluoroacetate ≥99%(HPLC) 130663-39-7 10 $231 2021-12-16 Buy
Tocris 1361 PD123319ditrifluoroacetate ≥99%(HPLC) 130663-39-7 50 $903 2021-12-16 Buy
Usbiological 462090 PD 123319 130663-39-7 10mg $439 2021-12-16 Buy
Usbiological 256179 PD 123319 ditrifluoroacetate 130663-39-7 10mg $480 2021-12-16 Buy
TRC P217705 PD123319 130663-39-7 10mg $140 2021-12-16 Buy
Product number Packaging Price Buy
1361 10 $231 Buy
1361 50 $903 Buy
462090 10mg $439 Buy
256179 10mg $480 Buy
P217705 10mg $140 Buy

PD 123319 ditrifluoroacetate Chemical Properties,Uses,Production

Uses

PD 123319 is a selective non-peptide angiotensin AT2 receptor antagonist.

Definition

ChEBI: An imidazopyridine consisting of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine having 4-(dimethylamino)-3-methylbenzyl, diphenylacetyl and carboxy and groups at positions 1, 5 and 6 respectively

Biological Activity

Potent, selective, non-peptide angiotensin AT 2 receptor antagonist. IC 50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.

References

[1] blankley c j, hodges j c, klutchko s r, et al. synthesis and structure-activity relationships of a novel series of non-peptide angiotensin ii receptor binding inhibitors specific for the at2 subtype. journal of medicinal chemistry, 1991, 34(11): 3248-3260.
[2] boulay g, servant g, luong t t, et al. modulation of angiotensin ii binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the dup-753-sensitive angiotensin ii receptor of bovine adrenal glomerulosa. molecular pharmacology, 1992, 41(4): 809-815.
[3] siragy h. angiotensin ii receptor blockers: review of the binding characteristics. the american journal of cardiology, 1999, 84(10): 3-8.

PD 123319 ditrifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

PD 123319 ditrifluoroacetate Suppliers

Global( 108)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32715 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 967 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39916 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 27792 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Biochempartner 		58
BOC Sciences 		58
Chongqing Chemdad Co., Ltd 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Dideu Industries Group Limited 		58
InvivoChem 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from PD 123319 ditrifluoroacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PD 123,319 DITRIFLUOROACETATE pictures 2019-07-06 PD 123,319 DITRIFLUOROACETATE
130663-39-7
 US $2.00 / kg 1kg 99% 100kg Career Henan Chemical Co

PD 123319 ditrifluoroacetate Spectrum

PD 123319 ditrifluoroacetate(130663-39-7)1HNMR

130663-39-7(PD 123319 ditrifluoroacetate)Related Search:

PD 173074 PD 166285 PD 166866 PD 0325901 xav-939
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L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID PD 123319 ditrifluoroacetate

1of3

1-[[4-(DIMETHYLAMINO)-3-METHYLPHENYL]METHYL]-5-(DIPHENYLACETYL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID DITRIFLUOROACETATE (3S)-9-[(4-DIMETHYLAMINO-3-METHYL-PHENYL)METHYL]-4-(2,2-DIPHENYLACETYL)-4,7,9-TRIAZABICYCLO[4.3.0]NONA-7,10-DIENE-3-CARBOXYLIC ACID PD 123,319 PD 123,319 DITRIFLUOROACETATE S(+)-1-[[4-(DIMETHYLAMINO)-3-METHYLPHENYL]METHYL]-5-(DIPHENYLACETYL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZOL[4,5-C]PYRIDINE-6-CARBOXYLIC ACID DITRIFLUOROACETATE PD 123,319 DITRIFLUOROACETATE POTENT AND SELECTIVE 1-((4-(Dimethylamino)-3-methylphenyl)methyl)-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4.5-c]pyridine-6-carboxyli pd 123,319 di(trifluoroacetate) salt s-(+)-1-[(4-(dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6α-carboxylic acid (6S)-1-[4-(Dimethylamino)-3-methylbenzyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid (6S)-1-[4-Dimethylamino-3-methylbenzyl]-5-diphenylacetyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6α-carboxylic acid 1H-Imidazo(4,5-C)pyridine-6-carboxylic acid, 1-((4-(dimethylamino)-3-methylphenyl)methyl)-5-(diphenylacetyl)-4,5,6,7-tetrahydro-, (S)- 1H-IMidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(diMethylaMino)-3-Methylphenyl]Methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-, (6S)- ditrifluoroacetate (S)-(+)-PD 123319 (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid PD123319 TFA 1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid PD123319, >=98% CS-953 PD-123319 TFA salt PD 123319 ditrifluoroacetate USP/EP/BP PD 123319 ditrifluor PD-123319 free base 130663-39-7 C31H32N4O32CF3CO2H Inhibitors Angiotensin