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1H-1,2,4-Triazole-3,5-diamine

1H-1,2,4-Triazole-3,5-diamine Structure
1H-1,2,4-Triazole-3,5-diamine structure
CAS No.
1455-77-2
Chemical Name:
1H-1,2,4-Triazole-3,5-diamine
Synonyms
3,5-DIAMINO-1,2,4-TRIAZOLE;GUANAZOLE;4H-1,2,4-TRIAZOLE-3,5-DIAMINE;nsc1895;NSC 1895;MC 51762;NCI-C04819;TIMTEC-BB SBB004371;3,5-diamino-s-triazol;Guanazole (VAN) (8CI)
CBNumber:
CB3756001
Molecular Formula:
C2H5N5
Molecular Weight:
99.09
MDL Number:
MFCD00005233
MOL File:
1455-77-2.mol
MSDS File:
SDS
Last updated:2023-10-19 17:32:03
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1H-1,2,4-Triazole-3,5-diamine Properties

Melting point 202-205 °C (lit.)
Boiling point 473.7±28.0 °C(Predicted)
Density 1.686±0.06 g/cm3(Predicted)
refractive index 1.7330 (estimate)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility H2O: clear to hazy
form powder
pka 12.10±0.40(Predicted)
color white
Water Solubility Soluble in water.
BRN 112467
Stability Stability Air sensitive. Reacts with acids and oxidizing agents.
InChIKey PKWIYNIDEDLDCJ-UHFFFAOYSA-N
CAS DataBase Reference 1455-77-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII I01TWM5267
NCI Drug Dictionary guanazole
NIST Chemistry Reference 3,5-Diamino-1,2,4-triazole(1455-77-2)
EPA Substance Registry System Guanazole (1455-77-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS09
Signal word  Warning
Hazard statements  H361fd-H373-H411
Precautionary statements  P202-P260-P273-P280-P308+P313-P391
Hazard Codes  Xn,Xi,C
Risk Statements  22-34
Safety Statements  36/37-45-36/37/39-27-26
WGK Germany  3
RTECS  XZ4535000
TSCA  Yes
HS Code  29339990
NFPA 704
0
1 0

1H-1,2,4-Triazole-3,5-diamine price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D26202 3,5-Diamino-1,2,4-triazole 98% 1455-77-2 25g $189 2024-03-01 Buy
Sigma-Aldrich D26202 3,5-Diamino-1,2,4-triazole 98% 1455-77-2 100g $683 2024-03-01 Buy
TCI Chemical D2587 3,5-Diamino-1,2,4-triazole >97.0%(T) 1455-77-2 5g $32 2024-03-01 Buy
TCI Chemical D2587 3,5-Diamino-1,2,4-triazole >97.0%(T) 1455-77-2 25g $128 2024-03-01 Buy
Alfa Aesar B22775 3,5-Diamino-1,2,4-triazole, 98+% 1455-77-2 5g $33.65 2024-03-01 Buy
Product number Packaging Price Buy
D26202 25g $189 Buy
D26202 100g $683 Buy
D2587 5g $32 Buy
D2587 25g $128 Buy
B22775 5g $33.65 Buy

1H-1,2,4-Triazole-3,5-diamine Chemical Properties,Uses,Production

Chemical Properties

colourless crystals or faintly yellow powder

Uses

3,5-Diamino-1,2,4-triazole is used as an inhibitor of DNA synthesis. It also serves as an antitumor agents in the treatment of epigenetically-based diseases. It acts as a corrosion inhibitor for copper.

Definition

ChEBI: An aromatic amine that is 1,2,4-triazole substituted at positions 3 and 5 by amino groups.

General Description

Colorless crystals.

Air & Water Reactions

1H-1,2,4-Triazole-3,5-diamine is sensitive to air. Dust can be explosive when suspended in air at specific concentrations. Water soluble.

Reactivity Profile

The triazoles, of which 1H-1,2,4-Triazole-3,5-diamine is a member, are a group of highly explosive materials that are sensitive to heat, friction, and impact. Sensitivity varies with the type of substitution to the triazole ring. The amine substituted derivatives, 1H-1,2,4-Triazole-3,5-diamine, tend not to be explosion sensitive. Metal chelated and halogen substitution of the triazol ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives. 1H-1,2,4-Triazole-3,5-diamine forms salts readily with acids.

Health Hazard

SYMPTOMS: 1H-1,2,4-Triazole-3,5-diamine is stable under normal laboratory conditions.

Fire Hazard

Flash point data for 1H-1,2,4-Triazole-3,5-diamine are not available. 1H-1,2,4-Triazole-3,5-diamine is probably combustible.

Safety Profile

Human systemic effects by intravenous route: leukopenia (reduced white blood cell count) and thrombo cytopenia (reduced blood platelet count). Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

The triazole crystallises from water or EtOH. [Beilstein 26 III/IV 1161.]

1H-1,2,4-Triazole-3,5-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

1H-3,4'-bi-1,2,4-triazol-5-amine(SALTDATA: FREE) 7-(2-THIENYL)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-AMINE N-(5-amino-1H-1,2,4-triazol-3-yl)acetamide(SALTDATA: FREE)

1H-1,2,4-Triazole-3,5-diamine Suppliers

Global( 328)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12471 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 6000 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21689 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Xi'an Kono chem co., Ltd., 		029-86107037 13289246953 info@konochemical.com China 2995 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49391 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Changzhou Ansciep Chemical Co., Ltd. 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Accela ChemBio Inc. 		58
Xi'an Kono chem co., Ltd., 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from 1H-1,2,4-Triazole-3,5-diamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1H-1,2,4-Triazole-3,5-diamine pictures 2023-10-19 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
 US $20.00-1.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
1H-1,2,4-Triazole-3,5-diamine pictures 2023-10-11 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
1H-1,2,4-Triazole-3,5-diamine pictures 2023-09-06 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
 US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.

1H-1,2,4-Triazole-3,5-diamine Spectrum

1H-1,2,4-Triazole-3,5-diamine(1455-77-2)Raman1H-1,2,4-Triazole-3,5-diamine(1455-77-2)IR

1455-77-2(1H-1,2,4-Triazole-3,5-diamine)Related Search:

1H-1,2,4-Triazole-3,5-diamine 3,5-DIAMINO-1,2,4-TRIAZOLE,3,5-diamino-1,3,5-triazole,3 5-DIAMINO-1 2 4-TRIAZOLE 98% 1,2,4-Triazole 3,5,7-TRIAMINO-1,2,4-TRIAZOLO[4,3-A]-1,3,5-TRIAZINE N3-(4-CHLOROPHENYL)-1H-1,2,4-TRIAZOLE-3,5-DIAMINE
N3,N3,N5,N5-TETRAMETHYL-1-([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 1-phenyl-1H-1,2,4-triazole-3,5-diamine 1-(4-FLUOROBENZYL)-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 1-(2,6-DICHLOROBENZYL)-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 1H-1,2,4-Triazole-3,5-diamine,N-propyl-(9CI)
N-phenyl-1H-1,2,4-triazole-3,5-diamine 1-[(4-METHOXYPHENYL)SULFONYL]-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE N3,N3,N5,N5-TETRAMETHYL-1-(4-METHYLBENZYL)-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 4H-1,2,4-Triazole-3,4-diamine,5-ethyl-N-methyl-N-(phenylmethylene)-(9CI) 5-METHYL-1,2,4-TRIAZOLE-3,4-DIAMINE
4H-1,2,4-Triazole-3,4-diamine 1-(4-BROMOBENZYL)-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 7-(4-BROMOPHENYL)-2-MORPHOLINO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE

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s-Triazole, 3,5-diamino- TIMTEC-BB SBB004371 1H-1,2,4-TRIAZOLE-3,5-DIAMINE 3,5-Diamino-1,2,4-triazole (Guanazole) 1H-1,2,4-Triazole-3,5-diamine (Guanazole) GUANETIDINEHEMISULPHATE 3,5-DIAMINO-1,2,4-TRIAZOLE, 98+% 2,3-Diamino-1H-1,2,4-triazole nsc1895 NSC 1895 NCI-C04819 MC 51762 3,5-Diamino-s-triazole 3,5-diamino-s-triazol 1,2,4-Triazolidine, 3,5-diimino- 3,5-DIAMINO-1H-1,2,4-TRIAZOLE 3-AMINO-1H-1,2,4-TRIAZOL-5-YLAMINE Guanazole (VAN) (8CI) (5-amino-2H-1,2,4-triazol-3-yl)amine Guanazole SynonyMs 1H-1,2,4-Triazole-3,5-diaMine 1,2,4-triazolidine-3,5-diiMine 3,5-Diamino-1H-1,2,4-triazole, Guanazole 3,5-DiaMino-1,2,4-triazole, 98% 25GR Guanazole 3,5-Diamino-1,2,4-triazole (Guanazole) 3,5-Diamino-1H-1,2,4-triazole 1H-1,2,4-triazole-3,5-diamine 3,5-Diamino-1,2,4-triazole, 98%, for synthesis 3,5-Diamino-1,2,4-triazole> GUANAZOLE 3,5-DIAMINO-1,2,4-TRIAZOLE 4H-1,2,4-TRIAZOLE-3,5-DIAMINE 1455-77-2 1455-72-2 Heterocyclic Building Blocks DIA - DIC Triazoles Building Blocks Analytical Standards Analytical Chromatography Product Catalog Alphabetic Building Blocks Chemical Synthesis Heterocyclic Building Blocks Triazoles