PHENDIMETRAZINE BITARTRATE
- CAS No.
- 50-58-8
- Chemical Name:
- PHENDIMETRAZINE BITARTRATE
- Synonyms
- sprx;metra;adipost;melfiat;plegine;prelu-2;Alphazine;phendimetrazinetartrate;PHENDIMETRAXINE TARTRATE;PHENDIMETRAZINE BITARTRATE
- CBNumber:
- CB3757053
- Molecular Formula:
- C20H29NO13
- Molecular Weight:
- 491.44
- MDL Number:
- MFCD00238764
- MOL File:
- 50-58-8.mol
- MSDS File:
- SDS
| Melting point | 182 °C |
|---|---|
| storage temp. | -20°C |
| form | A solid |
| FDA UNII | 6985IP0T80 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H332-H315-H301-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P310-P321-P330-P405-P501-P261-P271-P304+P340-P312 |
| RIDADR | UN 1992 6.1(3) / PGIII |
| HS Code | 2934910000 |
| Toxicity | LD50 intraperitoneal in mouse: 210mg/kg |
PHENDIMETRAZINE BITARTRATE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0003805 | PHENDIMETRAZINE BITARTRATE 95.00% | 50-58-8 | 100G | $4244.63 | 2021-12-16 | Buy |
| AHH | MT-57833 | Phendimetrazinebitartrate 98% | 50-58-8 | 50ml | $630 | 2021-12-16 | Buy |
| Chemtos | P-7804 | PhendimetrazineTartrate | 50-58-8 | 25mg | $1100 | 2021-12-16 | Buy |
PHENDIMETRAZINE BITARTRATE Chemical Properties,Uses,Production
Originator
Plegine, Ayerst, US ,1961
Uses
Appetite suppressant (systemic).
Manufacturing Process
A mixture of 61 grams 1-phenyl-1-oxo-2-(N-methyl-N-ethanolamino)-propane hydrochloride and 100 cc 98-100% formic acid was refluxed at the boiling point at atmospheric pressure for 45 minutes on an oil bath. Thereafter, the oil bath temperature was increased to 180°C and as much of the excess unreacted formic acid as possible was distilled off. A vigorous evolution of carbon dioxide developed during the distillation, which ceased after approximately 45 additional minutes. The honey-yellow syrup which remained as the distillation residue was worked up by admixing it with about six volumes of water and adjusting the aqueous mixture to alkaline reaction with concentrated sodium hydroxide. An oily phase separated out which was extracted with ether. The ether extract was washed with water and dried over potassium carbonate. The solvent was distilled off and the distillation residue was fractionally distilled in vacuo. The base boils at 132°-133°C at 12 mm. The yield was 93% of theory. Reaction with tartaric acid gave the final product.
The starting material is produced by reacting propiophenone with bromine and then reacting the α-bromopropiophenone produced with 2methylaminomethanol.
brand name
Bontril (Mallinckrodt); Bontril (Valeant); Melfiat (Numark).
Therapeutic Function
Antiobesity
General Description
The optically pure compound phendimetrazine tartrate,(2S,3S)-3,4-dimethyl-2-phenylmorpholine-L-(+)-tartrate(Plegine), is considered an effective anorexiant that is lessabuse prone than amphetamine. The stereochemistry of(+)phendimetrazine is as shown.
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An antihistamine. When heated to decomposition it emits toxic fumes of NOx.
PHENDIMETRAZINE BITARTRATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Hebei Duling International Trade Co. LTD | +8618712993135 | sales01@hbduling.cn | China | 15743 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9767 | 58 |
View Lastest Price from PHENDIMETRAZINE BITARTRATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | PHENDIMETRAZINE BITARTRATE
50-58-8
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
-
- PHENDIMETRAZINE BITARTRATE
50-58-8
- US $1.00 / KG
- 98%
- Career Henan Chemical Co