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(S)-(-)-PROPRANOLOL HYDROCHLORIDE

(S)-(-)-PROPRANOLOL HYDROCHLORIDE Structure
(S)-(-)-PROPRANOLOL HYDROCHLORIDE structure
CAS No.
4199-10-4
Chemical Name:
(S)-(-)-PROPRANOLOL HYDROCHLORIDE
Synonyms
S-PROPANOLOL;S-(-)-PROPANOLOL HCL;S(-)-PROPRANOLOL HCL;l-Propranolol chlorhydrate;l-Propranolol hydrochloride;(S)-PROPRANOLOL HYDROCHLORIDE;Levopropranolol hydrochloride;L-(-)-Propranolol hydrochloride;2S-(-)-PROPANOLOL HYDROCHLORIDE;(S)-(-)-PROPRANOLOL HYDROCHLORIDE
CBNumber:
CB4455695
Molecular Formula:
C16H22ClNO2
Molecular Weight:
295.8
MDL Number:
MFCD00064547
MOL File:
4199-10-4.mol
Last updated:2023-06-30 15:45:59
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(S)-(-)-PROPRANOLOL HYDROCHLORIDE Properties

Melting point 193-195 °C(lit.)
storage temp. 2-8°C
solubility ethanol: 10 mg/mL
form powder
optical activity [α]25/D 25.5°, c = 1.0 in ethanol(lit.)
Water Solubility Soluble to 100 mM in water
BRN 3574966
InChIKey ZMRUPTIKESYGQW-UQKRIMTDSA-N
CAS DataBase Reference 4199-10-4(CAS DataBase Reference)
FDA UNII YP6GDU0L78

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3
NFPA 704
0
3 0

(S)-(-)-PROPRANOLOL HYDROCHLORIDE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P8688 (S)-(?)-Propranolol hydrochloride ≥98% (TLC), powder 4199-10-4 100mg $111 2024-03-01 Buy
Sigma-Aldrich P8688 (S)-(?)-Propranolol hydrochloride ≥98% (TLC), powder 4199-10-4 500mg $449 2024-03-01 Buy
Cayman Chemical 17291 (S)-(-)-Propranolol (hydrochloride) ≥98% 4199-10-4 50mg $37 2024-03-01 Buy
Cayman Chemical 17291 (S)-(-)-Propranolol (hydrochloride) ≥98% 4199-10-4 100mg $68 2024-03-01 Buy
Cayman Chemical 17291 (S)-(-)-Propranolol (hydrochloride) ≥98% 4199-10-4 250mg $161 2024-03-01 Buy
Product number Packaging Price Buy
P8688 100mg $111 Buy
P8688 500mg $449 Buy
17291 50mg $37 Buy
17291 100mg $68 Buy
17291 250mg $161 Buy

(S)-(-)-PROPRANOLOL HYDROCHLORIDE Chemical Properties,Uses,Production

Description

(S)-(-)-Propranolol is the active enantiomer of propranolol, a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. It is also a non-specific serotonin receptor antagonist. Propanolol was one of the first β-adrenergic receptor blockers to be widely used in clinical practice for the treatment of hypertension, angina pectoris, and cardiac ischemia.

Chemical Properties

(S)-(-)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride

Uses

Antihypertensor;Beta-adrenergic blocking agent

Uses

active enantiomer, 5-HT1 receptor antagonist

Uses

The S-enantiomer of Propranolol (P831800). β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).

Biological Activity

More active enantiomer of the β -adrenoceptor antagonist propranolol ((RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride ).

Biochem/physiol Actions

(S)-(?)-Propranolol hydrochloride is biologically active enantiomer. It acts as β1 receptor antagonist in thalamocortical neurons. (S)-(?)-Propranolol hydrochloride elicits its inhibitory function on the β1 adrenoceptor in trigeminovascular pain pathway and serves as a preventive medicine in migraine.

storage

Store at RT

Purification Methods

The (+)-salt is the active isomer which blocks isoprenaline tachycardia and is a -adrenergic blocker. [Leclerc et al. Trends Pharmacol Sci 2 18 1981, Howe & Shanks Nature 210 1336 1966.]

(S)-(-)-PROPRANOLOL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-(-)-PROPRANOLOL HYDROCHLORIDE Suppliers

Global( 91)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Baoji Guokang Healthchem co.,ltd 		+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9427 58
BOC Sciences 		+16314854226 inquiry@bocsci.com United States 19743 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Hubei Jusheng Technology Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Baoji Guokang Healthchem co.,ltd 		58
BOC Sciences 		58
Nextpeptide Inc 		58
LEAP CHEM CO., LTD. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58

View Lastest Price from (S)-(-)-PROPRANOLOL HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(-)-PROPRANOLOL HYDROCHLORIDE pictures 2021-11-02 (S)-(-)-PROPRANOLOL HYDROCHLORIDE
4199-10-4
 US $166.00 / Kg/Bag 1Kg/Bag 99% 2000KG Baoji Guokang Healthchem co.,ltd

(S)-(-)-PROPRANOLOL HYDROCHLORIDE Spectrum

(S)-(-)-PROPRANOLOL HYDROCHLORIDE(4199-10-4)1HNMR(S)-(-)-PROPRANOLOL HYDROCHLORIDE(4199-10-4)IR(S)-(-)-PROPRANOLOL HYDROCHLORIDE(4199-10-4)Raman

4199-10-4((S)-(-)-PROPRANOLOL HYDROCHLORIDE)Related Search:

1-ETHOXYNAPHTHALENE (RS)-Propranolol hydrochloride,Propranolol Hydrochloride for pharmaceutical raw materials,DL-PROPRANOLOL HYDROCHLORIDE (S)-(-)-PROPRANOLOL HYDROCHLORIDE Propanolol 3-AMINO-1-PHENOXY-2-PROPANOL HYDROCHLORIDE, 98
2-(1-NAPHTHYLOXY) ETHANOL Propranolol hydrochloride R(+)-PROPRANOLOL HYDROCHLORIDE >98% (R)-4-Hydroxy Propranolol Hydrochloride,(S)-4-Hydroxy Propranolol Hydrochloride d-Propranolol hydrochloride,(R)-(+)-PROPRANOLOL HYDROCHLORIDE,(R)-PROPRANOLOL HYDROCHLORIDE
(S)-3-AMINO-1,2-DIHYDROXYPROPANE HYDROCHLORIDE CHEMBRDG-BB 5482082 1-METHYLAMINO-3-PHENOXY-PROPAN-2-OL AKOS BBS-00007965 (S)-3-ISOPROPYLAMINO-1,2-PROPANEDIOL
3-phenoxy-1-propanamine (S)-N-DESISOPROPYLPROPRANOLOL 1-AMINO-3-PHENOXY-PROPAN-2-OL

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2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (2S)- (9CI) 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (S)- L-(-)-Propranolol hydrochloride l-Propranolol chlorhydrate l-Propranolol hydrochloride S-(-)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol hydrochloride S-PROPANOLOL (S)-1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride (S)-(-)-1-(1-Methylethylamino)-3-naphthalen-1-yloxy-propan-2-ol hydrochloride (2S)-1-(1-Naphtyloxy)-3-(isopropylamino)-2-propanol·hydrochloric acid (2S)-1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol hydrochloride (2S)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol hydrochloride (S)-()-Propranolol hydrochloride,(S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride (2S)-(-)-Propanolol Hydrochloride≥ 95% (NMR) (S)-(-)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE (S)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE S-(-)-PROPANOLOL HCL S(-)-PROPRANOLOL HCL (S)-(-)-PROPRANOLOL HYDROCHLORIDE (S)-PROPRANOLOL HYDROCHLORIDE 2S-(-)-PROPANOLOL HYDROCHLORIDE (S)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride 2-Propanol, 1-(1-methylethyl)amino-3-(1-naphthalenyloxy)-, hydrochloride, (2S)- (S)()Propranolol hydrochloride,(S) ( ) Propranolol hydrochloride Levopropranolol hydrochloride 4199-10-4 C16H22ClNO2 Asymmetric Synthesis Chiral Building Blocks Amino Alcohols Organic Building Blocks Adrenoceptor Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals