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ChemicalBook >> CAS DataBase List >>1-(4-HYDROXYPHENYL)-2-THIOUREA

1-(4-HYDROXYPHENYL)-2-THIOUREA

1-(4-HYDROXYPHENYL)-2-THIOUREA Structure
1-(4-HYDROXYPHENYL)-2-THIOUREA structure
CAS No.
1520-27-0
Chemical Name:
1-(4-HYDROXYPHENYL)-2-THIOUREA
Synonyms
USAF B-75;4-HYDROXYPHENYLTHIOUREA;p-hydroxyphenylthiourea;N-(4-Hydroxyphenyl)thiourea;1-(4-hydroxyphenyl)thiourea;4-HYDROXYPHENYLTHIOUREA, 98+%;1-(p-hydroxyphenyl)-2-thio-ure;1-(4-HYDROXYPHENYL)-2-THIOUREA;Thiourea, N-(4-hydroxyphenyl)-;N-(4-Hydroxyphenyl)thiourea, 98+%
CBNumber:
CB4462400
Molecular Formula:
C7H8N2OS
Molecular Weight:
168.22
MDL Number:
MFCD00041186
MOL File:
1520-27-0.mol
Last updated:2023-07-12 17:08:55
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1-(4-HYDROXYPHENYL)-2-THIOUREA Properties

Melting point 214 °C
Boiling point 341.5±44.0 °C(Predicted)
Density 1.450±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 9.53±0.26(Predicted)
BRN 1102429
InChI InChI=1S/C7H8N2OS/c8-7(11)9-5-1-3-6(10)4-2-5/h1-4,10H,(H3,8,9,11)
InChIKey QICKOOCQSYZYQB-UHFFFAOYSA-N
SMILES N(C1=CC=C(O)C=C1)C(N)=S
CAS DataBase Reference 1520-27-0(CAS DataBase Reference)
FDA UNII U97KKG63Z2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Danger
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a
Risk Statements  22
Safety Statements  22-36/37
RTECS  YT5250000
HazardClass  IRRITANT
Toxicity mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,
NFPA 704
1
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1-(4-HYDROXYPHENYL)-2-THIOUREA price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar L12537 N-(4-Hydroxyphenyl)thiourea, 98+% 1520-27-0 1g $40.65 2024-03-01 Buy
Alfa Aesar L12537 N-(4-Hydroxyphenyl)thiourea, 98+% 1520-27-0 5g $116.65 2024-03-01 Buy
TRC H940080 1-(4-Hydroxyphenyl)thiourea 1520-27-0 1g $50 2021-12-16 Buy
SynQuest Laboratories 8667-1-22 1-(4-Hydroxyphenyl)-2-thiourea 1520-27-0 1g $51 2021-12-16 Buy
AK Scientific 4729AD 1-(4-Hydroxyphenyl)-2-thiourea 1520-27-0 250mg $70 2021-12-16 Buy
Product number Packaging Price Buy
L12537 1g $40.65 Buy
L12537 5g $116.65 Buy
H940080 1g $50 Buy
8667-1-22 1g $51 Buy
4729AD 250mg $70 Buy

1-(4-HYDROXYPHENYL)-2-THIOUREA Chemical Properties,Uses,Production

Uses

1-(4-Hydroxyphenyl)thiourea is an intermediate in the synthesis of (SKI II), a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.

1-(4-HYDROXYPHENYL)-2-THIOUREA synthesis

333-20-0
123-30-8
1520-27-0
Synthesis of 1-(4-HYDROXYPHENYL)-2-THIOUREA from Potassium thiocyanate and 4-Aminophenol

1-(4-HYDROXYPHENYL)-2-THIOUREA Preparation Products And Raw materials

Raw materials

N-Benzoyl-N'-(p-hydroxyphenyl)thiourea Thiourea, N,N'-bis(4-hydroxyphenyl)- (4-Hydroxyphenyl)dithiocarbamicacid,triethylaminesalt 4-HYDROXYPHENYLISOTHIOCYANATE Benzoyl isothiocyanate
4-Hydroxyaniline hydrochloride Potassium thiocyanate Sodium thiocyanate 4-Aminophenol

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Preparation Products

1-(4-HYDROXYPHENYL)-2-THIOUREA Suppliers

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
Unipharm pharmaceutical industry Co., Ltd
536-8266195 +8613953676784 lee@unipharm-sd.com China 1206 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10828 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11605 64
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32360 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94838 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109 market03@meryer.com China 40240 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30132 84
Supplier Advantage
Unipharm pharmaceutical industry Co., Ltd
58
Wuhan Chemwish Technology Co., Ltd 		58
Career Henan Chemica Co 		58
LEAP CHEM CO., LTD. 		58
Amadis Chemical Company Limited 		58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Mainchem Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84

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4-HYDROXYPHENYLTHIOUREA 1-(4-HYDROXYPHENYL)-2-THIOUREA 4-HYDROXYPHENYLTHIOUREA, 98+% USAF B-75 1-(p-hydroxyphenyl)-2-thio-ure p-hydroxyphenylthiourea 1-(4-hydroxyphenyl)thiourea N-(4-Hydroxyphenyl)thiourea N-(4-Hydroxyphenyl)thiourea, 98+% Thiourea, N-(4-hydroxyphenyl)- 1520-27-0