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MAST CELL DEGRANULATING PEPTIDE

CAS No.
32908-73-9
Chemical Name:
MAST CELL DEGRANULATING PEPTIDE
Synonyms
MCD;isulfide);MCD PEPTIDE;Peptide 401;IKCNCKRHVIKPHICRKICGKN-NH2;MCD PEPTIDE (APIS MELLIFERA);MAST CELL DEGRANULATING PEPTIDE;MAST CELL DEGRANULATING (MCD) PEPTIDE;mastcelldegranulatingpeptide(honeybee);MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA)
CBNumber:
CB4493264
Molecular Formula:
C110H192N40O24S4
Molecular Weight:
2587.24
MDL Number:
MFCD00167557
MOL File:
32908-73-9.mol
Last updated:2023-05-18 11:31:07

MAST CELL DEGRANULATING PEPTIDE Properties

Density 1.50±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  OQ5980000

MAST CELL DEGRANULATING PEPTIDE price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-7079 Peptide401 98.29% 32908-73-9 500ug $336 2021-12-16 Buy
Biorbyt Ltd orb99641 Mast Cell Degranulating peptide Greater than 98 % purified 32908-73-9 0.5mg $408 2021-12-16 Buy
ChemScene CS-7079 Peptide401 98.29% 32908-73-9 1mg $576 2021-12-16 Buy
Biorbyt Ltd orb99642 Mast Cell Degranulating peptide Greater than 98 % purified 32908-73-9 1mg $595 2021-12-16 Buy
American Custom Chemicals Corporation PEP0002440 MAST CELL DEGRANULATING PEPTIDE 95.00% 32908-73-9 0.5MG $726.73 2021-12-16 Buy
Product number Packaging Price Buy
CS-7079 500ug $336 Buy
orb99641 0.5mg $408 Buy
CS-7079 1mg $576 Buy
orb99642 1mg $595 Buy
PEP0002440 0.5MG $726.73 Buy

MAST CELL DEGRANULATING PEPTIDE Chemical Properties,Uses,Production

Biological Activity

Peptide 401 is a potent mast cell degranulation peptide derived from bee venom that inhibits vascular permeability.

in vivo

Peptide 401 substantially inhibits the oedema provoked by subplantar injection of carrageenin or intra-articular injection of turpentine in the rat. The ED 50 of 401 is c. 0.1 mg/kg. The anti-inflammatory effect is assessed by measurement of the increased 125 I-albumin content of an injected site in comparison with an uninjected contralateral site. Peptide 401 also suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, bradykinin, 5-hydroxytryptamine (5-HT), and prostaglandins). Peptide 401 (MCD peptide) contains 22 residues and occurs in the venom of the common European honey bee to the extent of about 2% by weight . It has powerful anti-inflammatory activity (at doses as low as 0.1 mg/kg) in a variety of animal models, ie, hind paw oedema in the rat induced by carrageenin or turpentine, adjuvant arthritis in the rat, and increased skin permeability in the rat resulting from subcut aneous injection of bradykinin, prostaglandin E1 kallikrein, histamine and 5-hydroxytryptamine (5-HT). It has a powerful degranulating effect on mast cells and involves the release of histamine and other pharmacologically active agents.

target

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MAST CELL DEGRANULATING PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

MAST CELL DEGRANULATING PEPTIDE Suppliers

Global( 60)Suppliers

serotonin

Histamine Receptor

Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15956 58
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2944 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33350 58
Shanghai Hanhong Scientific Co.,Ltd. 021-021-64543801 13764082696 2355241799@qq.com China 42982 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60

View Lastest Price from MAST CELL DEGRANULATING PEPTIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MAST CELL DEGRANULATING PEPTIDE pictures 2020-02-17 MAST CELL DEGRANULATING PEPTIDE
32908-73-9
US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co
H-ILE-LYS-+CYS-ASN-++CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-+CYS-ARG-LYS- ILE-++CYS-GLY-LYS-ASN-NH2 H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2 H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2 (RANDOM CYCLIZATION) IKCNCKRHVIKPHICRKICGKN-NH2 ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2 MAST CELL DEGRANULATING PEPTIDE MAST CELL DEGRANULATING PEPTIDE (APIS MELLIFERA) MAST CELL DEGRANULATING (MCD) PEPTIDE MCD PEPTIDE MCD PEPTIDE (APIS MELLIFERA) MCD isulfide) mastcelldegranulatingpeptide(honeybee) mastcelldegranulatingpeptide(honeybeereduced)cyclic(3-15),(5-19)-bis(d MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA) L-Ile-L-Lys-L-Cys(1)-L-Asn-L-Cys(2)-L-Lys-L-Arg-L-His-L-Val-L-Ile-L-Lys-L-Pro-L-His-L-Ile-L-Cys(1)-L-Arg-L-Lys-L-Ile-L-Cys(2)-Gly-L-Lys-L-Asn-NH2 Peptide 401 Mast Cell Degranulating (MCD) Peptide Peptide 401 L-Aspartamide, L-isoleucyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinylglycyl-L-lysyl-, cyclic (3→15),(5→19)-bis(disulfide) 32908-73-9 C110H192N40O24S4 Voltage-gated Ion Channels Ion Channels Potassium Channel Modulators Monovalent Ion Channels BioChemical Cell Signaling and Neuroscience Cell Biology