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PIMARIC ACID

CAS No.
127-27-5
Chemical Name:
PIMARIC ACID
Synonyms
Pimaric;NSC 2956;PIMARIC ACID;Pimaric Acid (>DextropiMaric Acid;Δ8(14)-PiMaric Acid;Pimaric acid (PiMA);Pimaric Acid (> 75%);Hexazinone Impurity 27;8(14),15-PiMaradien-18-oic Acid
CBNumber:
CB4506393
Molecular Formula:
C20H30O2
Molecular Weight:
302.45
MDL Number:
MFCD28369457
MOL File:
127-27-5.mol
Last updated:2023-05-25 18:01:10

PIMARIC ACID Properties

Melting point 217-219°
alpha D18 +74.7° (c = 0.4 in chloroform); D20 +87.3° (in chloroform)
Boiling point bp18 282°
Density 1.0434 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. Store at -20°C
solubility DMSO: soluble,Water: soluble
pka 4.68±0.60(Predicted)
LogP 6.731 (est)
Indirect Additives used in Food Contact Substances PIMARIC ACID
FDA 21 CFR 175.105
FDA UNII 88R98Z71NI
EPA Substance Registry System Pimaric acid (127-27-5)

PIMARIC ACID price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26062 Pimaric Acid 127-27-5 500μg $68 2022-04-27 Buy
Cayman Chemical 26062 Pimaric Acid 127-27-5 5mg $269 2022-04-27 Buy
Cayman Chemical 26062 Pimaric Acid 127-27-5 1mg $122 2022-04-27 Buy
Usbiological 286933 Pimaric acid 127-27-5 1mg $582 2021-12-16 Buy
TRC P445100 PimaricAcid(>75%) 127-27-5 10mg $1540 2021-12-16 Buy
Product number Packaging Price Buy
26062 500μg $68 Buy
26062 5mg $269 Buy
26062 1mg $122 Buy
286933 1mg $582 Buy
P445100 10mg $1540 Buy

PIMARIC ACID Chemical Properties,Uses,Production

Description

Pimaric acid is a resin acid that has been found in A. cordata and various pines. It reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs) in a concentration-dependent manner when used at concentrations ranging from 5 to 20 μM. Pimaric acid (10-20 μM) reduces nuclear expression and binding of the transcription factors NF-κB and AP-1 to the MMP-9 promoter in HASMCs. Pimaric acid also reduces TNF-α-induced HASMC migration to control levels when used at a concentration of 20 μg/ml.

Uses

A novel activators of large-conductance Ca2+-activated K+ channel α-subunit.

Definition

ChEBI: (+)-Pimaric acid is a diterpenoid.

PIMARIC ACID Preparation Products And Raw materials

Global( 68)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33350 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131980 58
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 6010 61

View Lastest Price from PIMARIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
		PIMARIC ACID pictures 2019-12-26 PIMARIC ACID
127-27-5
US $1.00 / KG 1KG 85.0-99.8% 20 tons Career Henan Chemical Co
  • 		PIMARIC ACID pictures
  • PIMARIC ACID
    127-27-5
  • US $1.00 / KG
  • 85.0-99.8%
  • Career Henan Chemical Co

PIMARIC ACID Spectrum

(1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-triMethyl-1-phenanthrenecarboxylic Acid 13α-Methyl-13-vinylpodocarp-8(14)-en-15-oic acid PIMARIC ACID 1-phenanthrenecarboxylicacid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahyd 7-trimethyl-,[1theta-(1alpha,4abeta,4balpha,7beta,10aalpha)]-ro-4a 13-alpha-methyl-13-vinylpodocarp-8(14)-en-15-oic acid 1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,4bS,7S,10aR)- 8(14),15-PiMaradien-18-oic Acid DextropiMaric Acid NSC 2956 PiMara-8(14),15-dien-19-oic Acid Δ8(14)-PiMaric Acid Pimaric Acid (Contains 10-25% Sandaracopimaric Acid) Pimaric Acid (> Pimaric Acid (> 75%) Pimaric Hexazinone Impurity 27 Pimaric acid (PiMA) 127-27-5 Activators Aliphatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals