ChemicalBook >> CAS DataBase List >>SPERMINE NONOATE
SPERMINE NONOATE
- CAS No.
- 136587-13-8
- Chemical Name:
- SPERMINE NONOATE
- Synonyms
- NOC-22;SPER/NO;SPERMINE NONOATE;Spermine NONOate,97%;SpermineNONOate,SPER/NO;Spermine Bis(NO) Adduct;SPERMINE/NITRIC OXIDE COMPLEX;SPERMINE BIS (NITRIC OXIDE) ADDUCT;SPERMINE/NITRIC OXIDE COMPLEX (SPER/NO);Spermine-Nitric oxide complex hydrate
- CBNumber:
- CB5128354
- Molecular Formula:
- C10H26N6O2
- Molecular Weight:
- 262.35
- MDL Number:
- MFCD00210215
- MOL File:
- 136587-13-8.mol
Last updated:2023-04-23 13:52:06
| Melting point | 105-107°C |
|---|---|
| Boiling point | 405.6°C (rough estimate) |
| Density | 1.0879 (rough estimate) |
| refractive index | 1.7000 (estimate) |
| storage temp. | -20°C |
| solubility | methanol: ≥1mg/mL |
| form | White solid |
| pka | 5.47±0.69(Predicted) |
| color | white |
| Stability | Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use. |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|
SPERMINE NONOATE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S150 | Spermine–Nitric oxide complex source of nitric oxide | 136587-13-8 | 25mg | $197 | 2021-12-16 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 10mg | $39 | 2024-03-01 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 25mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 50mg | $172 | 2024-03-01 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 100mg | $302 | 2024-03-01 | Buy |
SPERMINE NONOATE Chemical Properties,Uses,Production
Description
Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.? ? The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37 °C, or 230 min at room temperature.1? ? Dissociation is essentially instantaneous at a pH of 5.0.
Chemical Properties
Off-White Solid
Uses
A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.
General Description
Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t?) of NO release = 230 min (PBS, pH 7.4, 22°C).
Biological Activity
A stable complex of nitric oxide and spermine used to generate a controlled release of nitric oxide in solution (EC 50 = 6.2 μ M for relaxation of rabbit aorta, and t=39 min at 37℃, pH 7.4, aqueous solution).
Biochem/physiol Actions
Product does not compete with ATP.
References
1) Keefer et al. (1996), “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol., 268 281
SPERMINE NONOATE Preparation Products And Raw materials
SPERMINE NONOATE Suppliers
Global( 70)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12990 | 57 | |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 400-400-400-9004166 18616739031 | 3007523370@qq.com | China | 52712 | 58 |
View Lastest Price from SPERMINE NONOATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-04 | Spermine NONOate
136587-13-8
|
US $48.00-40.00 / KG | 1KG | 99% | 200tons | Guangzhou Sunton Biotechnology Co., Ltd. |
-
- Spermine NONOate
136587-13-8
- US $48.00-40.00 / KG
- 99%
- Guangzhou Sunton Biotechnology Co., Ltd.
136587-13-8(SPERMINE NONOATE)Related Search:
(Z)-1-[N-[3-AMINOPROPYL]-N-[4-(3-AMINOPROPYL-AMMONIO)BUTYL]-AMINO]-DIAZEN-1-IUM-1,2-DIOLATE
(Z)-1-[N-(3-AMMONIOPROPYL)-N-[4-(3-AMINOPROPYLAMMONIO) BUTYL]-AMINO]DIAZEN-1-IUM-1,2-DIOLATE
SPERMINE BIS (NITRIC OXIDE) ADDUCT
SPERMINE/NITRIC OXIDE COMPLEX
SPERMINE NONOATE
SPER/NO
NOC-22
N-[4-[1-(3-AMINOPROPYL)-2-HYDROXY-2-NITROSOHYDRAZINO]BUTYL]-1,3-PROPANEDIAMINE
N-(2-AMINOETHYL)-N-(2-HYDROXY-2-NITROSOHYDRAZINO)-1,2-ETHYLENEDIAMINE
N-(2-AMINOETHYL)-N-(2-HYDROXY-3-NITROSOHYDRAZINO)-1,2-ETHYLENEDIAMINE
SPERMINE/NITRIC OXIDE COMPLEX (SPER/NO)
SpermineNONOate,SPER/NO
N1-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazinyl]butyl]-1,3-propanediamine
Spermine Bis(NO) Adduct
SPER/NO, Spermine NONOate, N-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazino]butyl]-1,3-propanediamine
Spermine-Nitric oxide complex hydrate
Spermine NONOate,97%
N'-(3-aMinopropyl)-N'-(4-((3-aMinopropyl)aMino)butyl)-N-hydroxynitrous hydrazide hydrate
Spermine NONOate - CAS 136587-13-8 - Calbiochem
N'-(3-Aminopropyl)-N'-(4-((3-aminopropyl)amino)butyl)-N-hydroxynitrous hydrazide
1,3-Propanediamine, N1-[4-[1-(3-aminopropyl)-2-hydroxy-2-nitrosohydrazinyl]butyl]-
136587-13-8
C10H26N6O2H2O
C10H26N6O2
Application Index
Cell Signaling Enzymes
Biochemicals and Reagents
BioChemical
NO Donors
Nitric Oxide Metabolism
Enzymes, Inhibitors, and Substrates
Nitric Oxide Reagents
Amines