ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
- CAS No.
- 4450-98-0
- Chemical Name:
- ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
- Synonyms
- 1-Ebpc;CP-10668;Nsc 229530;Aldose Reductase,inhibit,EBPC,Inhibitor;1-Benzyl-4-bydroxy-5-oxo-3-pyrroline-3-carboxylic Acid Ethyl Ester;1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester;2,5-Dihydro-4-hydroxy-5-oxo-1-(phenylMethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester;1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-, ethyl ester
- CBNumber:
- CB51373216
- Molecular Formula:
- C14H15NO4
- Molecular Weight:
- 261.27
- MDL Number:
- MFCD00179167
- MOL File:
- 4450-98-0.mol
| Melting point | 135-136 °C |
|---|---|
| Boiling point | 479.8±45.0 °C(Predicted) |
| Density | 1.340±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: ≥10mg/mL |
| form | white powder |
| pka | 4.50±1.00(Predicted) |
| FDA UNII | MW8LQ9P85C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| NFPA 704 |
|
ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PZ0140 | EBPC ≥98% (HPLC) | 4450-98-0 | 5mg | $105 | 2024-03-01 | Buy |
| Sigma-Aldrich | PZ0140 | EBPC ≥98% (HPLC) | 4450-98-0 | 25mg | $505 | 2024-03-01 | Buy |
| Cayman Chemical | 14183 | EBPC ≥98% | 4450-98-0 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 14183 | EBPC ≥98% | 4450-98-0 | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 14183 | EBPC ≥98% | 4450-98-0 | 10mg | $139 | 2024-03-01 | Buy |
ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate Chemical Properties,Uses,Production
Description
The human aldose reductase AKR1B1 is considered the rate limiting enzyme of the polyol pathway responsible for the conversion of glucose into sorbitol. It also acts as a highly efficient PGF2α synthase in response to interleukin-
Uses
A highly specific aldose reductase inhibitor that has been shown to enhance HeLa cell sensitivity to chemotherapeutic drugs.
Definition
ChEBI: Ethyl 1-benzyl-3-hydroxy- 2-oxo[5H]pyrrole-4-carboxylate is a pyrroline and a carboxylic acid.
ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7893 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Aikon International Limited | 025-66113011 13155353615 | qzhang@aikonchem.com | China | 15396 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |