5'-DEOXYADENOSINE
- CAS No.
- 4754-39-6
- Chemical Name:
- 5'-DEOXYADENOSINE
- Synonyms
- 5′-dAdo;5'-DEOXYADENOSINE;5’-deoxy-adenosin;5'-DEOXYADENOSINE;Adenosine, 5'-deoxy-;2'-Deoxycytidine Monohydrate(2'-dC ? H?O);9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine;6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine;(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol;(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol
- CBNumber:
- CB5163003
- Molecular Formula:
- C10H13N5O3
- Molecular Weight:
- 251.24
- MDL Number:
- MFCD00056003
- MOL File:
- 4754-39-6.mol
- MSDS File:
- SDS
Melting point | 210-212 °C |
---|---|
Boiling point | 595.0±60.0 °C(Predicted) |
Density | 1.93±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 15 mg/ml |
form | A crystalline solid |
pka | 13.29±0.70(Predicted) |
InChIKey | XGYIMTFOTBMPFP-KQYNXXCUSA-N |
EWG's Food Scores | 1 |
FDA UNII | 2U0TYC8Y5A |
5'-DEOXYADENOSINE price More Price(16)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D1771 | 5′-Deoxyadenosine methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate | 4754-39-6 | 25mg | $264 | 2024-03-01 | Buy |
Cayman Chemical | 29619 | 5''-Deoxyadenosine | 4754-39-6 | 10mg | $40 | 2024-03-01 | Buy |
Cayman Chemical | 29619 | 5''-Deoxyadenosine | 4754-39-6 | 250mg | $541 | 2024-03-01 | Buy |
Cayman Chemical | 29619 | 5''-Deoxyadenosine | 4754-39-6 | 50mg | $158 | 2024-03-01 | Buy |
Cayman Chemical | 29619 | 5''-Deoxyadenosine | 4754-39-6 | 100mg | $296 | 2024-03-01 | Buy |
5'-DEOXYADENOSINE Chemical Properties,Uses,Production
Description
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis.
Uses
5′-Deoxyadenosine has been used:
- as a standard in mass spectroscopy
- as an inhibitor for screening thymidine phosphorylase activity
- as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay
Definition
ChEBI: A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.
Biochem/physiol Actions
5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.
5'-DEOXYADENOSINE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7154 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9980 | 58 |
Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |