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ChemicalBook >> CAS DataBase List >>4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Structure
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER structure
CAS No.
191102-87-1
Chemical Name:
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
Synonyms
GGTI-2147;GGTI-2147 (GGTI2147);TUQRZGWNDBXSNP-SANMLTNESA-N;Geranylgeranyl transferase inhibitor-2147;4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER;L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
CBNumber:
CB5766770
Molecular Formula:
C28H30N4O3
Molecular Weight:
470.56
MDL Number:
MFCD22581512
MOL File:
Mol file
Last updated:2023-07-14 17:49:10
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4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Properties

Boiling point 710.6±60.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
solubility Soluble in DMSO
pka 13.22±0.46(Predicted)
form Solid
Sensitive Light Sensitive & Hygroscopic

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 345885 GGTI-2147 - CAS 191102-87-1 - Calbiochem A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I). 191102-87-1 250μG $245 2024-03-01 Buy
Alfa Aesar J65022 GGTI-2147 191102-87-1 100microg $591 2021-12-16 Buy
TRC G368900 GGTI-2147 191102-87-1 5mg $1470 2021-12-16 Buy
TRC G368900 GGTI-2147 191102-87-1 0.1mg $115 2021-12-16 Buy
Product number Packaging Price Buy
345885 250μG $245 Buy
J65022 100microg $591 Buy
G368900 5mg $1470 Buy
G368900 0.1mg $115 Buy

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Chemical Properties,Uses,Production

Uses

GGTI-2147 is an inhibitors of protein geranylgeranyltransferase-I and protein prenylation. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast and increases cytosolic accumulation of Rac1 and elicites significant inhibition of GSIS from INS 832/13 cells.

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd 		+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518 sales@alabiochem.com China 995 59
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Alabiotech Inc. 001-619-354-5251 sales@alabiotech-e.com United States 972 60
Alpha Biopharmaceuticals Co., Ltd 0411-39042497 sales@alphabiopharm.com China 1951 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55791 58
Supplier Advantage
Alpha Biopharmaceuticals Co., Ltd 		58
TargetMol Chemicals Inc. 		58
Nextpeptide Inc 		58
J & K SCIENTIFIC LTD. 76
Alabiochem Tech.Co., Ltd. 59
VDM Biochemicals 64
Shanghai TaoSu Biochemical Technology Co., Ltd. 58
Alabiotech Inc. 60
Alpha Biopharmaceuticals Co., Ltd 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
GGTI-2147 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER TUQRZGWNDBXSNP-SANMLTNESA-N GGTI-2147 (GGTI2147) L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester Geranylgeranyl transferase inhibitor-2147 191102-87-1 A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I). Amino Acids & Derivatives, Chiral Reagents, Heterocycles, Inhibitors Other enzyme inhibitors and activators