DL-ERYTHRO-DIHYDROSPHINGOSINE
- CAS No.
- 3102-56-5
- Chemical Name:
- DL-ERYTHRO-DIHYDROSPHINGOSINE
- Synonyms
- DIHYDROSPHINGOSINE;D-ERYTHRO-SPHINGANINE;D-ERYTHRO-DIHYDROSPHINGOSINE;DL-ERYTHRO-1,3-DIHYDROXY-2-AMINOOCTADECANE;DL-SPHINGANINE;D,L-ERYTHRO-SPHINGANINE;DL-ERYTHRO-DIHYDROSPHINGOSINE;DIHYDROSPHINGOSINE, D-ERYTHRO;D-ERYTHRO-SPHINGOSINE, DIHYDRO-;D-ERTYTHRO-SPHINGANINE, C18 CHAIN
- CBNumber:
- CB6139144
- Molecular Formula:
- C18H39NO2
- Molecular Weight:
- 301.51
- MDL Number:
- MFCD00079141
- MOL File:
- 3102-56-5.mol
- MSDS File:
- SDS
| Melting point | 70-72°C |
|---|---|
| Boiling point | 446.2±25.0 °C(Predicted) |
| Density | 0.927±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | chloroform/methanol (9:1): 20 mg/mL, clear, colorless to faintly yellow |
| form | Solid |
| pka | 12.57±0.45(Predicted) |
| color | white |
| Water Solubility | Soluble in water (partly miscible), chloroform, 100% warm ethanol (25 mg/ml), warm DMSO (25 mg/ml), and methanol. |
| InChI | InChI=1/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/s3 |
| InChIKey | OTKJDMGTUTTYMP-LHIQYTEENA-N |
| SMILES | C(O)[C@@H](N)[C@@H](O)CCCCCCCCCCCCCCC |&1:2,4,r| |
| CAS DataBase Reference | 3102-56-5(CAS DataBase Reference) |
DL-ERYTHRO-DIHYDROSPHINGOSINE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J62103 | DL-erythro-Dihydrosphingosine | 3102-56-5 | 50mg | $486 | 2021-12-16 | Buy |
| Cayman Chemical | 24367 | DL-erythro/threo Sphinganine (d18:0) ≥98% | 3102-56-5 | 25mg | $184 | 2024-03-01 | Buy |
| TRC | D151745 | DL-erythro-Dihydrosphingosine | 3102-56-5 | 2.5mg | $100 | 2021-12-16 | Buy |
| Usbiological | 255144 | Dihydrosphingosine | 3102-56-5 | 10mg | $418 | 2021-12-16 | Buy |
| ApexBio Technology | B6434 | (2S,3S)-2-aminooctadecane-1,3-diol | 3102-56-5 | 10mg | $223 | 2021-12-16 | Buy |
DL-ERYTHRO-DIHYDROSPHINGOSINE Chemical Properties,Uses,Production
Description
DL-erythro Sphinganine (d18:0) is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate . Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well as in some cancers. This product is a mixture of sphinganine (d18:0) , L-erythro sphinganine (d18:0) , D-threo sphinganine (d18:0) , and L-threo sphinganine (d18:0). [Matreya, LLC. Catalog No. 1324]
Chemical Properties
White Powder
Uses
Biosynthetic precursor of sphingosine. Inhibits protein kinase C
Uses
DL-erythro-Dihydrosphingosine is an inhibitor of PKC (protein kinase C). This compound also blocks PLA2 (phospholipases A2) and the D-sphingosine precursor.
Definition
ChEBI: 2-aminooctadecane-1,3-diol is an aminodiol that is octadecane bearing two hydroxy substituents at positions 1 and 3 as well as an amino substituent at position 2. It is a sphingoid and an aminodiol.
Biological Activity
Protein kinase C inhibitor.
storage
-20°C (desiccate)
Purification Methods
Purify it by recrystallisation from pet ether/EtOAc or CHCl3. The (±)-N-dichloroacetyl derivative has m 142-144o (from MeOH). [Shapiro et al. J Am Chem Soc 80 2170 1958, Shapiro & Sheradsky J Org Chem 28 2157 1963.] The D-isomer crystallises from pet ether/Et2O and has m 78.5-79o, [] 28 +6o (CHCl3/MeOH, 10:1). [Grob & Jenny Helv Chim Acta 35 2106 1953, Jenny & Grob Helv Chim Acta 36 1454 1953, Beilstein 4 I 448, 4 II 757, 4 III 854, 4 IV 1887.]
DL-ERYTHRO-DIHYDROSPHINGOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
DL-ERYTHRO-DIHYDROSPHINGOSINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28659 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 8393 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 | sales@zhswyy.com | China | 242 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
View Lastest Price from DL-ERYTHRO-DIHYDROSPHINGOSINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-11 | Phytosphingosine 55%/D-erythro-Dihydrosphingosine 20% mixture
3102-56-5
|
US $0.00-0.00 / kg | 0.10000000149011612kg | 75% | 2000kgs | Chongqing Zhihe Biopharmaceutical Co., Ltd. |
-
- Phytosphingosine 55%/D-erythro-Dihydrosphingosine 20% mixture
3102-56-5
- US $0.00-0.00 / kg
- 75%
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
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