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1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER

CAS No.
28246-87-9
Chemical Name:
1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
Synonyms
Ethyl 1-cyanocyclobutane-1-carboxylate;ethyl 1-cyanocyclobutanecarboxylate;1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER;1-Cyano-Cyclobutanecarboxylic Acid Ethyl Este;Cyclobutanecarboxylic acid, 1-cyano-, ethyl ester;*Guaiacol Impurity 1 (Guaiacol EP Impurity A)(Pyrocatechol);(Z)-3-hydroxy-1-[5-(thiophen-2-ylmethyl)-2-furanyl]-3-(1H-1,2,4-triazol-5-yl)-2-propen-1-one
CBNumber:
CB6801258
Molecular Formula:
C8H11NO2
Molecular Weight:
153.18
MDL Number:
MFCD04114273
MOL File:
28246-87-9.mol
Last updated:2023-04-27 16:27:43

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Properties

Boiling point 215.5-216 °C(Press: 762 Torr)
Density 1.09±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P280-P301+P312-P302+P352
HS Code  2926907090

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E926323 Ethyl1-cyanocyclobutane-1-carboxylate 28246-87-9 25mg $45 2021-12-16 Buy
TRC E926323 Ethyl1-cyanocyclobutane-1-carboxylate 28246-87-9 250mg $75 2021-12-16 Buy
AK Scientific 2753AB Ethyl1-cyanocyclobutanecarboxylate 28246-87-9 1g $80 2021-12-16 Buy
SynQuest Laboratories 4237-1-00 Ethyl 1-cyanocyclobutanecarboxylate 98% 28246-87-9 1g $106 2021-12-16 Buy
AK Scientific 2753AB Ethyl1-cyanocyclobutanecarboxylate 28246-87-9 10g $420 2021-12-16 Buy
Product number Packaging Price Buy
E926323 25mg $45 Buy
E926323 250mg $75 Buy
2753AB 1g $80 Buy
4237-1-00 1g $106 Buy
2753AB 10g $420 Buy

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Uses

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical and pharmaceutical production process.

Synthesis

Synthesis_28246-87-9
4-(9>-cyclopentyl-5'-methyl-6>-oxo-5>,6>,8>,9>- tetrahydrospiro[cyclobutane-l,7'-pyrimido[4,5-b][l,4]diazepine]-2'-ylamino)-3- methoxybenzoic acid; [0521] Ethyl 1-cyanocyclobutanecarboxylate; To a solution of sodium ethoxide (21wt% in EtOH, 5.79 rnL, 15.5 mmol) in EtOH (25 mL), was added ethyl cyanoacetate(1.12 mL, 10.5 mmol), followed shortly thereafter by 1,1-dibromopropane (1.12 mL, 10 mmol). The reaction mixture was refluxed for 3 hrs. It was then concentrated, and diluted to ethyl acetate. The organic layer was washed with NaHCCh, brine, water, dried over Na2SO4 and concentrated in vacuo to obtain ethyl 1-cyanocyclobutanecarboxylate (1.17 g, 74% yield) as a red liquid. It was used directly for next step reaction.

105-56-6
109-64-8
28246-87-9
Synthesis of 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER from Ethyl cyanoacetate and 1,3-Dibromopropane

1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 81)Suppliers
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Changzhou Ditong Chemical Co.,Ltd
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Changzhou AniKare Pharmatech Co., Ltd.
+86-0519-8359-8696 +8618018249389 sales@anikare.com China 8472 58

View Lastest Price from 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER pictures 2020-01-13 1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
28246-87-9
US $1.00 / KG 1KG 98%-99.9% 100kg Career Henan Chemical Co
1-CYANOCYCLOBUTANECARBOXYLIC ACID ETHYL ESTER ethyl 1-cyanocyclobutanecarboxylate Cyclobutanecarboxylic acid, 1-cyano-, ethyl ester (Z)-3-hydroxy-1-[5-(thiophen-2-ylmethyl)-2-furanyl]-3-(1H-1,2,4-triazol-5-yl)-2-propen-1-one 1-Cyano-Cyclobutanecarboxylic Acid Ethyl Este Ethyl 1-cyanocyclobutane-1-carboxylate *Guaiacol Impurity 1 (Guaiacol EP Impurity A)(Pyrocatechol) 28246-87-9