Rutaecarpine
- CAS No.
- 20575-76-2
- Chemical Name:
- Rutaecarpine
- Synonyms
- Ai3-51108;Nsc 255317;Brn 2116874;Rutaecarpine;3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA);1,1'-Hexamethylenebis[3,3-dimethylurea];Urea, 1,1'-hexamethylenebis(3,3-dimethyl-;1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea);N,N''-1,6-Hexanediylbis[N',N'-dimethylurea];Urea, N,N''-1,6-hexanediylbis[N',N'-dimethyl-
- CBNumber:
- CB6975933
- Molecular Formula:
- C12H26N4O2
- Molecular Weight:
- 258.36
- MDL Number:
- MFCD00025668
- MOL File:
- 20575-76-2.mol
- MSDS File:
- SDS
| Boiling point | 512.3±33.0 °C(Predicted) |
|---|---|
| Density | 1.021±0.06 g/cm3(Predicted) |
| pka | 13.98±0.46(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | 5Q7CEJ9UES |
Rutaecarpine price More Price(1)
Rutaecarpine Chemical Properties,Uses,Production
Biological Functions
Rutaecarpine also inhibits accumulation of macrophages and cholesterol in atherosclerotic lesions and increases cholesterol excretion in other animal models. Additionally, rutaecarpine inhibits hypoxia-induced production of ROS and lactate dehydrogenase and suppresses apoptosis in myocardiocytes. In other cellular models, rutaecarpine decreases corticosterone production, potentially through inhibition of cAMP, 3β-hydroxysteroid dehydrogenase, and 11β-hydroxylase activity.
Biological Activity
Rutaecarpine is an indoloquinazoline alkaloid originally found in Evodia; it exhibits anti-inflammatory, anti-atherosclerotic, cardioprotective, anorexigenic, and anti-obesity activities. Rutaecarpine inhibits COX-2 and also decreases food intake, weight gain, and serum glucose, leptin, and insulin levels in vivo by inhibiting expression of neuropeptide Y and AgRP.
Mechanism of action
Rutaecarpine also inhibits production of ROS, NO, and iNOS, potentially through inhibition of NADPH oxidase. In macrophages, rutaecarpine inhibits arachidonic acid release and decreases production of prostaglandin E2 (PGE2); in other in vitro models, it inhibits collagen-stimulated formation of thromboxane B2 and inosine monophosphate.
Rutaecarpine Preparation Products And Raw materials
Raw materials
Preparation Products
Rutaecarpine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27644 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52861 | 58 |
| Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +8618374838656 | sales@staherb.cn | China | 1025 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 400-400-400-9004166 18616739031 | 3007523370@qq.com | China | 52712 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 4008210725 4008210725 | malulu@leyan.com | China | 55023 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9947 | 58 |
| Shanghai Moqi Biological Technology Co., LTD | 021-38218169 13341702378 | 190129269@qq.com | China | 9115 | 58 |
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View Lastest Price from Rutaecarpine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-06-03 | Rutaecarpine
20575-76-2
|
US $500.00-400.00 / kg | 1kg | 98% | 1000 | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2020-02-04 | Rutaecarpine
20575-76-2
|
US $1.00 / KG | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
-
- Rutaecarpine
20575-76-2
- US $500.00-400.00 / kg
- 98%
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Rutaecarpine
20575-76-2
- US $1.00 / KG
- 98% HPLC
- Career Henan Chemical Co