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METHYL-D3-MALONIC ACID

CAS No.
42522-59-8
Chemical Name:
METHYL-D3-MALONIC ACID
Synonyms
NSC 2520-d3;Isosuccinic Acid-d3;MethylMalonic Acid-d3;METHYL-D3-MALONIC ACID;Methyl-d?-malonic acid;[2H3]-Methylmalonic Acid;Methyl-d3-propanedioic Acid;2-Methylpropanedioic acid D3;2-METHYL-D3-PROPANEDIOIC ACID;1,1-Ethanedicarboxylic Acid-d3
CBNumber:
CB7715949
Molecular Formula:
C4H3D3O4
Molecular Weight:
121.11
MDL Number:
MFCD00144783
MOL File:
42522-59-8.mol
Last updated:2023-06-08 09:03:04

METHYL-D3-MALONIC ACID Properties

Melting point 134-136 °C(lit.)
Flash point 2 °C
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H332-H315-H319-H335
Precautionary statements  P261-P264-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn,F
Risk Statements  20/22-36/37/38-36-20/21/22-11
Safety Statements  26-36-36/37-16
RIDADR  UN 1648 3 / PGII
WGK Germany  3
NFPA 704
0
3 0

METHYL-D3-MALONIC ACID price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M-105 Methyl-D3-malonic acid solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 42522-59-8 1mL $180 2024-03-01 Buy
Sigma-Aldrich 490318 Methyl-d3-malonic acid 98 atom % D 42522-59-8 250mg $820 2024-03-01 Buy
TRC M318862 MethylmalonicAcid-d3 42522-59-8 10mg $120 2021-12-16 Buy
Usbiological 017011 Methylmalonic Acid-d3 42522-59-8 10mg $382 2021-12-16 Buy
American Custom Chemicals Corporation RDL0013270 METHYL-D3-MALONIC ACID 95.00% 42522-59-8 5MG $499.68 2021-12-16 Buy
Product number Packaging Price Buy
M-105 1mL $180 Buy
490318 250mg $820 Buy
M318862 10mg $120 Buy
017011 10mg $382 Buy
RDL0013270 5MG $499.68 Buy

METHYL-D3-MALONIC ACID Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

An isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.

Uses

Methyl-d3-malonic acid is an isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-depend ent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.

General Description

Methylmalonic acid, a malonic acid derivative, is a vital intermediate in the metabolism of fat and proteins and plays a key role in energy metabolism. Elevated methylmalonic acid levels can be caused by an inborn error of metabolism leading to methylmalonic aciduria or indicate early vitamin B<sub>12</sub> deficiency. This internal standard is suitable for quantitation of methylmalonic acid levels by LC/MS or GC/MS in newborn screening and clinical testing applications to test for methylmalonic acidemia and diagnose vitamin B<sub>12</sub> deficiency.

METHYL-D3-MALONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9685 58
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1977 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Artis Biotech Co. Ltd. 19138486554 18582380095 sales@artisbio.com China 2804 58
Chengdu Novel Biomedical Co., Ltd. 028-85255396 18302801538 cdnovell@163.com China 2251 58
Nanjing Haolv Biotechnology Co.,Ltd 025-84622273 02584622273; kexin.zhou@haolvbiotech.com China 3021 58
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841 amber@biochempartner.com China 3063 58
METHYL-D3-MALONIC ACID, 98 ATOM % D METHYLMALONIC ACID (METHYL-D3) METHYL-D3-MALONIC ACID 2-METHYL-D3-PROPANEDIOIC ACID 1,1-Ethanedicarboxylic Acid-d3 Isosuccinic Acid-d3 Methyl-d3-propanedioic Acid NSC 2520-d3 Methyl-D3-malonic acid solution MethylMalonic Acid-d3 2-Methylpropanedioic acid D3 Methylmalonic Acid-[d3] (Solution) [2H3]-Methylmalonic Acid 2-(trideuteriomethyl)propanedioic acid Methyl-d?-malonic acid 42522-59-8 CD3CHCO2H2 C4H3D3O4 CD3CHCOOH2 Stable Isotopes BioChemical Alphabetical Listings Alphabetical Listings M Stable Isotopes Aliphatics Intermediates & Fine Chemicals Isotope Labelled Compounds Metabolites & Impurities Pharmaceuticals