Cyclopentadecanolide
- CAS No.
- 106-02-5
- Chemical Name:
- Cyclopentadecanolide
- Synonyms
- Exaltolide;PENTADECANOLIDE;OXACYCLOHEXADECAN-2-ONE;Exaltolide Total;ω-Pentadecalactone;PENTALIDE;Pentadecalactone;Pentadecan-15-olide;OMEGA-PENTADECALACTONE;Thibetolide
- CBNumber:
- CB9207055
- Molecular Formula:
- C15H28O2
- Molecular Weight:
- 240.38
- MDL Number:
- MFCD00039667
- MOL File:
- 106-02-5.mol
- MSDS File:
- SDS
Melting point | 34-38 °C(lit.) |
---|---|
Boiling point | 137 °C2 mm Hg(lit.) |
Density | 0.918 g/mL at 25 °C(lit.) |
vapor pressure | 0.085Pa at 25℃ |
refractive index | 1.4700 |
FEMA | 2840 | OMEGA-PENTADECALACTONE |
Flash point | >230 °F |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform, Ethyl Acetate, Methanol (Slightly) |
form | Solid |
color | White to Off-White |
Odor | at 10.00 % in dipropylene glycol. musk animal powdery natural fruity |
Odor Type | musk |
Water Solubility | Soluble in alcohol, dipropylene glycol. Insoluble in water. |
Merck | 14,3910 |
JECFA Number | 239 |
BRN | 143710 |
LogP | 5.79 at 25℃ |
Substances Added to Food (formerly EAFUS) | OMEGA-PENTADECALACTONE |
CAS DataBase Reference | 106-02-5(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | OK17S3S98K |
NIST Chemistry Reference | Oxacyclohexadecan-2-one(106-02-5) |
EPA Substance Registry System | Oxacyclohexadecan-2-one (106-02-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS09 |
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Signal word | Warning | |||||||||
Hazard statements | H410 | |||||||||
Precautionary statements | P273-P391-P501 | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | RN9775000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29322090 | |||||||||
Toxicity | Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Levenstein, 1974). | |||||||||
NFPA 704 |
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Cyclopentadecanolide price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | W284009 | ω-Pentadecalactone ≥98%,FG | 106-02-5 | 1kg | $322 | 2024-03-01 | Buy |
Sigma-Aldrich | W284009 | ω-Pentadecalactone ≥98%,FG | 106-02-5 | 5kg | $806 | 2024-03-01 | Buy |
Sigma-Aldrich | 419133 | Pentadecanolide 98% | 106-02-5 | 25g | $41.22 | 2024-03-01 | Buy |
Sigma-Aldrich | 419133 | Pentadecanolide 98% | 106-02-5 | 100g | $103.2 | 2024-03-01 | Buy |
Sigma-Aldrich | W284009 | ω-Pentadecalactone ≥98%,FG | 106-02-5 | 100g | $95.8 | 2023-01-07 | Buy |
Cyclopentadecanolide Chemical Properties,Uses,Production
Chemical Properties
ω-Pentadecalactone has an extraordinarily persistent, musk-like odor.
Chemical Properties
white crystalline low melting solid
Chemical Properties
Cyclopentadecanolide occurs in small quantities in, for example, angelica root oil. It forms colorless crystals (mp 37–38°C) with a delicate, musk-like odor.
Occurrence
Originally reported found in the essential oil from angelica roots.
Uses
Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.
Uses
Pentadecanolide may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization. It may be employed as starting reagent for the synthesis of terminally-branched iso-fatty acids (iso-C15-C17).
Uses
As a fixative in perfumery.
Definition
ChEBI: Cyclopentadecanolide is a macrolide.
Preparation
The main industrial syntheses start from compounds produced from cyclododecatriene: either by ring expansion of cyclododecanone or by depolymerization of polyesters of 15-hydroxypentadecanoic acid (from 1,12-dodecanediol).
Aroma threshold values
Detection: 1 to 4 ppb
Taste threshold values
Taste characteristics at 75 ppm: vanilla bean, powdery helioropine, creamy and licorice.
Synthesis Reference(s)
Tetrahedron Letters, 34, p. 6107, 1993 DOI: 10.1016/S0040-4039(00)61741-0
The Journal of Organic Chemistry, 50, p. 2394, 1985 DOI: 10.1021/jo00213a044
General Description
Pentadecanolide is one of the major components, isolated from the root of Angelica archangelica L., species. It is a synthetic musk, which exists as a widespread contaminant in the environment.
Flammability and Explosibility
Non flammable
Trade name
Macrolide® (Symrise), Exaltolide®, Exaltolide®Total (Firmenich), Pentalide (Soda Aromatic).
Purification Methods
It has been recrystallised from MeOH (4 parts) at -15o. [Hundieck
Cyclopentadecanolide Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12470 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6011 | 58 |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 2999 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9340 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8829 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
View Lastest Price from Cyclopentadecanolide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-23 | Cyclopentadecanolide
106-02-5
|
US $85.00-25.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | ||
2024-04-27 | Cyclopentadecanolide
106-02-5
|
US $20.00 / kg | 1kg | 99.9% | 200000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd | ||
2023-11-04 | Cyclopentadecanolide
106-02-5
|
US $0.00-0.00 / kg | 1kg | 99% | 50000kg | Hebei Kingfiner Technology Development Co.Ltd |
- Cyclopentadecanolide
106-02-5
- US $85.00-25.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
- Cyclopentadecanolide
106-02-5
- US $20.00 / kg
- 99.9%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
- Cyclopentadecanolide
106-02-5
- US $0.00-0.00 / kg
- 99%
- Hebei Kingfiner Technology Development Co.Ltd
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