ChemicalBook >> CAS DataBase List >>N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
- CAS No.
- 78538-74-6
- Chemical Name:
- N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
- Synonyms
- LSU-65;FG 7142;Zk-31906;ZK 39106;β-CCA methylamide;N-Methyl-β-carboline-3-carboxamide;N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE;B-carboline-3-carboxylic acid N-*methylamide;4-b)indole-3-carboxamide,n-methyl-9h-pyrido(;n-methyl-9h-pyrido(3,4-b)indole-3-carboxamide
- CBNumber:
- CB9228957
- Molecular Formula:
- C13H11N3O
- Molecular Weight:
- 225.25
- MDL Number:
- MFCD00055075
- MOL File:
- 78538-74-6.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Boiling point | 576.3±30.0 °C(Predicted) |
|---|---|
| Density | 1.328±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ethanol: 1 mg/mL |
| form | A crystalline solid |
| pka | 13.44±0.46(Predicted) |
| color | light tan |
| EWG's Food Scores | 1 |
| FDA UNII | 60PO70N1BP |
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E006 | β-Carboline-3-carboxylic acid N-methylamide | 78538-74-6 | 100mg | $282 | 2024-03-01 | Buy |
| Sigma-Aldrich | E006 | β-Carboline-3-carboxylic acid N-methylamide | 78538-74-6 | 500mg | $974 | 2024-03-01 | Buy |
| Cayman Chemical | 29183 | FG-7142 ≥98% | 78538-74-6 | 50mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 29183 | FG-7142 ≥98% | 78538-74-6 | 100mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 29183 | FG-7142 | 78538-74-6 | 10mg | $59 | 2021-12-16 | Buy |
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Chemical Properties,Uses,Production
Description
FG 7142 (ZK 39106; LSU-65) is a nonselective benzodiazepine inverse agonist with high affinity (Ki= 91 nM) for the α1 subunit-containing GABAA receptor. FG 7142 also modulates GABA-induced chloride flux (EC50=137 nM) at GABAA receptors expressing the α1 subunit. FG 7142 increases tyrosine hydroxylation and leads to upregulation of β-adrenergic receptors in mouse cerebral cortex.
Uses
FG 7142 is a benzodiazepine inverse agonist anxiogenic compound.
Definition
ChEBI: N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide is a member of beta-carbolines.
Biological Activity
Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β -adrenoceptors in mouse cerebral cortex.
Biochem/physiol Actions
Benzodiazepine inverse receptor agonist; potent anxiogenic agent.
storage
Store at RT
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Suppliers
Global( 59)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
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1of4
4-b)indole-3-carboxamide,n-methyl-9h-pyrido(
n-methyl-9h-pyrido(3,4-b)indole-3-carboxamide
FG 7142
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
B-carboline-3-carboxylic acid N-*methylamide
N-METHYL-B-CARBOLINE-3-CARBOXAMIDE (FG-7 142)
beta-carboline-3-carboxylic acid N-methylamide
β-Carboline-3-carboxylic acid N-methylamide
β-CCA methylamide, FG-7142, N-Methyl-β-carboline-3-carboxamide
9H-Pyrido(3,4-B)indole-3-carboxamide, N-methyl-
Zk-31906
β-CCA methylamide
9H-beta-Carboline-3-carboxylic acid methylamide
LSU-65
ZK 39106
N-Methyl-β-carboline-3-carboxamide
ZK39106,nucleus accumben,inverse agonist,GABA Receptor,LSU65,LSU 65,dopaminergic,FG 7142,GABAA receptor,inhibit,FG-7142,Gamma-aminobutyric acid Receptor,ZK-39106,FG7142,tyrosine hydroxylase,γ-Aminobutyric acid Receptor,Inhibitor
78538-74-6
GABA/Glycine receptor